[MORPHOMETRIC CHARACTERISTICS OF SUBSTANTIA NIGRA CELLULAR STRUCTURES OF THE HUMAN BRAIN].

V N Sal’kov, R M Khudoyerkov, D N Voronkov
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Abstract

Neurons and glial cells were studied by means of computerassisted morphometry in the segments of the ventral and dorsal regions of the compact part of the substantia nigra (CPSN) of the brain. The material obtained at autopsy from 6 males and 3 females aged from 52 to 87 years. It was found that in segments of the ventral CPSN region the neuronal cell bodies and nuclei were larger than those in the segments of the dorsal region. The numerical density of neurons and gliocytes in the ventrolateral segment was higher than in the segments of the dorsal region. In the ventromedial segment the glial index was lower than in the segments of the dorsal region. The morphometric differences found between CPSN segments must be taken into account in the assessment of the morphological changes in substantia nigra of the brain, due to both age involution or pathological process.

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[人脑黑质细胞结构的形态学特征]。
用计算机辅助形态测量法研究了大脑黑质致密部腹侧和背侧的神经元和神经胶质细胞。材料来自6名男性和3名女性,年龄从52岁到87岁。结果表明,在背侧CPSN区域,腹侧CPSN区域的神经元胞体和细胞核比背侧CPSN区域的大。腹外侧节段神经元和胶质细胞的数值密度高于背侧节段。腹内段的神经胶质指数低于背侧部分。在评估脑黑质的形态学变化时,必须考虑到CPSN段之间的形态计量学差异,这是由于年龄退化或病理过程造成的。
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