Wedged gel pad for bowel manipulation during MR-guided high-intensity focused ultrasound therapy to treat uterine fibroids: a case report.

Journal of therapeutic ultrasound Pub Date : 2018-11-28 eCollection Date: 2018-01-01 DOI:10.1186/s40349-018-0116-4
Teija Sainio, Gaber Komar, Jani Saunavaara, Visa Suomi, Kirsi Joronen, Antti Perheentupa, Antti Viitala, Roberto Blanco Sequeiros
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引用次数: 9

Abstract

Background: Magnetic resonance guided high-intensity focused ultrasound (MR-HIFU) therapy is not feasible in all patients with uterine fibroids because of limiting anatomical factors such as scar tissue, bowel loops or other obstacles in the sonication path. These may prevent the treatment or limit the treatment window, and therefore, also the volume where HIFU therapy can be delivered. Bowel loops present a particular problem because of bowel gas bubbles and hard particles which may cause reflection or absorption of ultrasound energy, potentially leading to thermal damage and even bowel perforation. Most commonly used techniques for bowel repositioning are bladder and/or rectum filling but these are not always sufficient to reposition the bowel loops. With more efficient bowel repositioning technique, the number of eligible patients for MR-HIFU treatment could be increased, and therapy efficacy be improved in cases where bowel loops limit the treatment window.

Case presentation: A wedged exterior gel pad was used in two patients presented with in total of four symptomatic fibroids undergoing MR-HIFU treatment when bladder and/or rectum filling was not sufficient to reposition the bowel loops. No severe adverse effects were observed in these cases. The non-perfused volume ratios (NPVs) immediately after treatment were 86% and 39% for the first patient, and 3% for the second patient.

Conclusions: Our preliminary experience suggests that the use of a wedged gel pad during MR-HIFU treatment could be an effective tool to manipulate the bowels in cases where the bladder and/or rectum filling is not sufficient to reposition the bowel loops. A wedged gel pad could also be used in other situations to achieve better treatment coverage to the uterine fibroid.

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在核磁共振引导下高强度聚焦超声治疗子宫肌瘤过程中使用楔形凝胶垫进行肠操作1例报告。
背景:磁共振引导下的高强度聚焦超声(MR-HIFU)治疗并非适用于所有子宫肌瘤患者,因为超声路径中存在瘢痕组织、肠袢或其他障碍等解剖学因素的限制。这些可能会阻止治疗或限制治疗窗口,因此也限制了HIFU治疗的容量。肠袢是一个特别的问题,因为肠内的气泡和硬颗粒可能会引起超声波能量的反射或吸收,潜在地导致热损伤甚至肠穿孔。最常用的肠道重新定位技术是膀胱和/或直肠填充,但这些并不总是足以重新定位肠环。采用更有效的肠道重新定位技术,可以增加符合MR-HIFU治疗条件的患者数量,并且在肠环限制治疗窗口的情况下提高治疗效果。病例介绍:在膀胱和/或直肠填充不足以重新定位肠袢的情况下,有2例患者总共有4个症状性肌瘤,接受MR-HIFU治疗,使用楔形外部凝胶垫。在这些病例中未观察到严重的不良反应。1例患者治疗后立即非灌注体积比(npv)分别为86%和39%,2例患者为3%。结论:我们的初步经验表明,在MR-HIFU治疗中,当膀胱和/或直肠填充物不足以重新定位肠袢时,使用楔形凝胶垫可能是操纵肠道的有效工具。楔形凝胶垫也可用于其他情况,以达到更好的治疗覆盖子宫肌瘤。
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