[Association between osteoporosis and atherosclerosis in dyslipidemia.]

Nobuyuki Tai, Daisuke Inoue
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引用次数: 1

Abstract

Age-related osteoporosis and atherosclerosis is promoted by life style-related diseases such as dyslipidemia and diabetes mellitus. Common factors pathophysiologically involved in both osteoporosis and vascular calcification include senescent cells and osteoprotegerin(OPG). Dyslipidemia may impair both osteoclast and osteoblast function,thereby causing osteoporosis. Statins may have favorable effect on bone. Some anti-osteoporotic medications have also been suggested to show protective effect from atherosclerosis.
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[血脂异常患者骨质疏松与动脉粥样硬化的关系]
与生活方式有关的疾病,如血脂异常和糖尿病,可促进与年龄有关的骨质疏松症和动脉粥样硬化。参与骨质疏松和血管钙化的常见病理生理因素包括衰老细胞和骨保护素(OPG)。血脂异常可损害破骨细胞和成骨细胞的功能,从而引起骨质疏松。他汀类药物可能对骨骼有益。一些抗骨质疏松药物也被认为对动脉粥样硬化有保护作用。
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