The Content of ROS in Blood Lymphocytes of Healthy Individuals, Individuals Irradiated as a Result of Chernobyl Disaster and Patients with Prostate Cancer.

I I Pelevina, A V Aleshchenko, M M Antoshchina, V A Biryukov, A B Karpycheva, O B Karyakin, L I Krikunova, O V Ktitorova, L S Mkrtchyan, M F Nikonova, I V Oradovskaya, Y G Paschenkova, E V Reva
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Abstract

The ROS concentration and proliferation activity (Ki67 expression.marker) have been studied in the periphery blood lymphocytes of Moscow and Obninsk citizens, donors, Chernobyl disaster liquidators, inhabitants of the region contaminated after Chernobyl disaster (Klincy) and individuals with prostate cancer. It was shown that ROS concentration in lymphocytes of the liquidators and residents of the polluted region was lowered. But in lymphocytes of patients with tumors the ROS content was higher in comparison with the control. The cell content with Ki67 expression in lymphocytes of the individuals resided in the polluted region and tumor patients was lowered.

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健康人、切尔诺贝利事故受伤者和前列腺癌患者血液淋巴细胞中ROS的含量
本文研究了莫斯科和奥布宁斯克市民、献血者、切尔诺贝利灾难清理者、切尔诺贝利灾难后污染地区居民(Klincy)和前列腺癌患者外周血淋巴细胞中ROS浓度和增殖活性(Ki67表达标志物)的变化。结果表明,清除者和污染地区居民淋巴细胞中ROS浓度降低。但肿瘤患者淋巴细胞中ROS含量高于对照组。污染区个体和肿瘤患者淋巴细胞中表达Ki67的细胞含量降低。
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