Direct oral anticoagulants in oral surgery: a prospective cohort.

Q3 Medicine Minerva stomatologica Pub Date : 2020-12-01 Epub Date: 2020-07-21 DOI:10.23736/S0026-4970.20.04389-7

Amanda L Rocha, Sicilia R Oliveira, Alessandra F Souza, Denise V Travassos, Lucas G Abreu, Daniel D Ribeiro, Tarcília A Silva

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引用次数: 2

Abstract

Background: Quantitative assessment of bleeding in dental extractions is rarely reported in the literature. The assessment of bleeding might provide additional evidence to predict and minimize postoperative outcomes. The aim of this study was to evaluate the pattern of bleeding in individuals taking direct oral anticoagulants (DOACs) submitted to dental extractions.

Methods: Intraoperative bleeding was evaluated by using total collected bleeding corrected by absorbance reading (dental bleeding score). To monitoring bleeding episodes from the day of surgery, this cohort was followed up until the seventh postoperative day.

Results: Forty-five procedures were performed in three comparative groups, patients under DOACs, individuals taking vitamin K antagonists (VKAs) and without anticoagulant therapy. No bleeding events were observed in procedures carried out in individuals of the DOAC group. Additional hemostatic measures were required in two procedures in the VKA group and one in the non-anticoagulated group. The dental bleeding scores obtained for the DOAC and VKA groups were similar.

Conclusions: Our data suggest that the DOAC therapy did not result in increased bleeding outcomes in this sample.

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口腔外科直接口服抗凝剂:一项前瞻性队列研究。

背景:文献中很少报道拔牙出血的定量评估。出血的评估可能为预测和减少术后结果提供额外的证据。本研究的目的是评估直接口服抗凝剂(DOACs)的个体在拔牙时出血的模式。方法:术中出血采用吸光读数校正的总出血(牙出血评分)进行评价。为了监测从手术当天开始的出血事件，该队列随访至术后第7天。结果:在三个比较组中进行了45例手术，分别是DOACs患者、服用维生素K拮抗剂(VKAs)的患者和未进行抗凝治疗的患者。DOAC组患者在手术过程中未见出血事件。2例VKA组和1例非抗凝组需要额外止血措施。DOAC组和VKA组牙出血评分相似。结论:我们的数据表明，DOAC治疗并未导致该样本出血结局增加。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Minerva stomatologica DENTISTRY, ORAL SURGERY & MEDICINE-

CiteScore

1.50

自引率

0.00%

发文量

期刊介绍： The journal Minerva Stomatologica publishes scientific papers on dentistry and maxillo-facial surgery. Manuscripts may be submitted in the form of editorials, original articles, review articles, case reports, therapeutical notes, special articles and letters to the Editor. Manuscripts are expected to comply with the instructions to authors which conform to the Uniform Requirements for Manuscripts Submitted to Biomedical Editors by the International Committee of Medical Journal Editors (www.icmje.org). Articles not conforming to international standards will not be considered for acceptance.