Why Do We Need Serological Tests for Severe Acute Respiratory Syndrome Coronavirus-2 Diagnosis?

Abstract

Considering the COVID-19 emerging and rapidly evolving situation associated with increased levels of mortality and infectivity risks, the detection and identification of new tests in a fast, safe, and accurate measures would have a high impact regarding prompt clinical and epidemiological management decisions. The combination of real-time polymerase chain reaction and the immunoglobulin class M-immunoglobulin class G antibody serology testing can be a powerful strategy for more accurate severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection diagnosis with less false results slipping through the cracks. The following viewpoint is describing the immunological response to SARS-Cov-2 infection and its implication in the selection of the appropriate diagnosis tools.