Comparison of glycaemic control and anthropometric parameters before and after Ramadan fasting in a selected cohort of patients with type 2 diabetes mellitus in Sri Lanka.

IF 0.3 Q3 MEDICINE, GENERAL & INTERNAL Ceylon Medical Journal Pub Date : 2020-12-31 DOI:10.4038/cmj.v65i4.9276

Mohamed Shafras, Lakshika Monaragala, Isha Samarakkody, Rafeek Ahamed, Lakshika Nawarathna, Mohamed Sanas, Charles Antonypillai

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引用次数: 2

Abstract

Introduction: The majority of Sri Lankan Moors fast during Ramadan. This may have an effect on their glycaemic control and anthropometric parameters. However, limited information exists about the impact of Ramadan fasting on diabetes in Sri Lanka.

Objectives: The main objective of this study was to investigate the effect of Ramadan fasting on glycaemic control and anthropometric parameters in patients with type 2 diabetes mellitus (T2DM). Patients were also observed for symptoms of hypoglycaemia, timing and association with different antidiabetic agents.

Methods: One hundred and twenty Sri Lankan Moors with T2DM were recruited for this study. Biochemical investigations and anthropometric parameters were done before and after Ramadan fasting. The statistical analysis was done with paired t test to compare glycaemic control and anthropometric parameters before and after Ramadan.

Results: There was a significant decrease in body weight (mean body weight 66.17 to 65.52 kg; p= < 0.001) and waist circumference (93.84 to 92.16cm; p= < 0.001). However, the glycaemic control worsened in all patients during Ramadan with rise in mean fructosamine value of 354.1 to 996.9µmol/L. Out of 104 participants 43 participants experienced symptoms of hypoglycaemia.

Conclusions: The current study showed an improvement in the body weight and waist circumference during Ramadan fasting, however the glycaemic control has been worsened. More follow-up studies are warranted in order to draw a conclusion on the effect of Ramadan fasting in glycaemic control and anthropometric parameters in diabetes patients.

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斯里兰卡2型糖尿病患者斋月禁食前后血糖控制和人体测量参数的比较

简介:大多数斯里兰卡摩尔人在斋月期间斋戒。这可能对他们的血糖控制和人体测量参数有影响。然而，关于斋月禁食对斯里兰卡糖尿病的影响的信息有限。目的:本研究的主要目的是探讨斋月禁食对2型糖尿病(T2DM)患者血糖控制和人体测量参数的影响。还观察了患者的低血糖症状，时间和与不同抗糖尿病药物的关联。方法:选取120名患有2型糖尿病的斯里兰卡摩尔人作为研究对象。在斋月禁食前后进行生化调查和人体测量参数测定。统计分析采用配对t检验比较斋月前后血糖控制和人体测量参数。结果:患者体重明显下降(平均体重66.17 ~ 65.52 kg;P = < 0.001)和腰围(93.84 ~ 92.16cm;P = < 0.001)。然而，斋月期间，所有患者的血糖控制都恶化了，果糖胺的平均值从354.1上升到996.9µmol/L。在104名参与者中，43名参与者出现了低血糖症状。结论:目前的研究显示，斋月禁食期间体重和腰围有所改善，但血糖控制恶化。为了得出斋月禁食对糖尿病患者血糖控制和人体测量参数的影响的结论，需要更多的随访研究。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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Ceylon Medical Journal MEDICINE, GENERAL & INTERNAL-

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期刊介绍： The Ceylon Medical Journal, is the oldest surviving medical journal in Australasia. It is the only medical journal in Sri Lanka that is listed in the Index Medicus. The CMJ started life way back in 1887 as the organ of the Ceylon Branch of the British Medical Association. Except for a brief period between 1893 and 1904 when it ceased publication, the CMJ or its forbear, the Journal of the Ceylon Branch of the British Medical Association, has been published without interruption up to now. The journal"s name changed to the CMJ in 1954.