[Tendencies of prescriptions for neuralgic pain in National Suruga Sanatorium (leprosy), Japan during last 11 years].

Q4 Medicine Japanese Journal of Leprosy Pub Date : 2009-09-01 DOI:10.5025/hansen.78.293
Akatsuki Yamada, Munekatsu Horita, Kazuaki Shindo, Yutaka Ishida, Mitsuyoshi Maeda
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Abstract

The number of ex-leprosy patients has reduced rapidly who were forced to be admitted under leprosy prevention/segregation law and are staying at national sanatoriums with different disabilities due to different physical and social reasons for long time in Japan. Most of them have been of clinically cured status for decades after effective chemotherapy. Some have still been suffering from acute or chronic neuralgic pains which are supposed to be long standing consequences of nerve damage of leprosy and getting medications for long period. Pharmacy department of National Suruga Sanatorium has studied the amount of prescriptions of some medicines for last 11 years, which were thought to be prescribed for pain including neuralgic pain. There seem to be some tendencies of medications during last decade. VitaminB12 (Mecobalamine) is one of the commonest drugs for neuralgic pain at this sanatorium and the amount of prescription had almost been unchanged through the years. Prescription of non-steroid anti-inflammatory drugs (NSAIDs) increased year by year, which may reflect the increasing age of ex-patients who need more pain killers for their painful joints or back. Loxoprofen is the most popular pain killer here and increased by ten times for last decade. The number of prescription for Pentazocine and Hydroxyzine Hydrochloride injection increased for last several years, which reflects a few patients who were still suffering from severe chronic neuralgia for years. It is desirable that a standard regimen for chronic neuralgic pain as a consequence of nerve impairment in leprosy will be developed as soon as possible.

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[日本国立骏河疗养院(麻风病)近11年神经痛处方趋势分析]。
在日本,根据麻风病预防/隔离法被迫入院的麻风病前患者数量迅速减少,他们因各种身体和社会原因长期住在国立疗养院。经有效化疗后,多数已临床治愈数十年。有些人仍然患有急性或慢性神经痛,这应该是麻风病神经损伤和长期服用药物的长期后果。国立骏鹤疗养院药科对过去11年里被认为是治疗神经痛等疼痛的部分药物的处方量进行了调查。近十年来,药物治疗似乎出现了一些趋势。维生素b12(甲钴胺)是这家疗养院治疗神经痛最常见的药物之一,多年来处方的数量几乎没有变化。非甾体抗炎药(NSAIDs)的处方逐年增加,这可能反映了前患者年龄的增长,他们需要更多的止痛药来治疗关节或背部疼痛。洛索洛芬是这里最受欢迎的止痛药,在过去十年里增加了十倍。戊唑嗪盐酸羟嗪注射液的处方数近年来有所增加,反映了少数患者多年来仍患有严重的慢性神经痛。麻风病神经损伤引起的慢性神经痛的标准治疗方案应尽快制定。
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来源期刊
Japanese Journal of Leprosy
Japanese Journal of Leprosy Medicine-Dermatology
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