Discrimination of inter-crystal scattering events by signal processing for the X'tal cube PET detector.

IF 1.7 Q3 RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING Radiological Physics and Technology Pub Date : 2023-12-01 Epub Date: 2023-10-02 DOI:10.1007/s12194-023-00740-3
Munetaka Nitta, Fumihiko Nishikido, Naoko Inadama, Yoshiyuki Hirano, Taiga Yamaya
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Abstract

Inter-crystal scattering (ICS) events cause degradation of the contrast in PET images. We developed the X'tal cube PET detector with submillimeter spatial resolution, which consisted of a segmented LYSO scintillator and 96 MPPCs. For this high spatial resolution PET detector, the ICS event was not negligible. In this study, we proposed a method to discriminate the ICS events and showed its feasibility by the following method. For each 96 MPPC, we measured the mean and standard deviation of the peak in the pulse height distribution obtained by the photoabsorption events in a scintillator pixel. Every time a newly detected event was identified as the segment, we monitored the reduced chi-square value that was calculated with the pulse height and the prepared mean and the standard deviation for each 96 MPPC. Since the pulse height caused by the photoabsorption event resulted in a small reduced chi-square value, we could eliminate the ICS events by setting a threshold on the reduced chi-square value. We carried out both a Monte Carlo simulation and a scanning experiment. By the simulation, we confirmed that the threshold of the reduced chi square significantly discriminated the ICS event. We obtained the response function by a scanning experiment with a 0.2 mm slit beam of 511 keV gamma-ray. The standard deviation of the response function was improved from 1.6 to 1.06 mm by eliminating the ICS events. The proposed method could significantly eliminate the ICS events and retain the true events.

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X’tal cube PET探测器晶体间散射事件的信号处理判别。
晶体间散射(ICS)事件导致PET图像中对比度的降低。我们开发了具有亚毫米空间分辨率的X’tal cube PET探测器,该探测器由分段LYSO闪烁体和96个MPPC组成。对于这种高空间分辨率的PET探测器,ICS事件不容忽视。在本研究中,我们提出了一种识别ICS事件的方法,并通过以下方法证明了其可行性。对于每个96MPPC,我们测量了通过闪烁体像素中的光吸收事件获得的脉冲高度分布中的峰值的平均值和标准偏差。每次新检测到的事件被识别为片段时,我们都会监测减少的卡方值,该值是用每个96 MPPC的脉冲高度、准备的平均值和标准偏差计算的。由于光吸收事件引起的脉冲高度导致较小的卡方值降低,我们可以通过在卡方值的降低上设置阈值来消除ICS事件。我们进行了蒙特卡罗模拟和扫描实验。通过仿真,我们证实了减少卡方的阈值显著地区分了ICS事件。我们通过用511keV伽马射线的0.2mm狭缝束的扫描实验获得了响应函数。通过消除ICS事件,响应函数的标准偏差从1.6 mm提高到1.06 mm。所提出的方法可以显著地消除ICS事件并保留真实事件。
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来源期刊
Radiological Physics and Technology
Radiological Physics and Technology RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING-
CiteScore
3.00
自引率
12.50%
发文量
40
期刊介绍: The purpose of the journal Radiological Physics and Technology is to provide a forum for sharing new knowledge related to research and development in radiological science and technology, including medical physics and radiological technology in diagnostic radiology, nuclear medicine, and radiation therapy among many other radiological disciplines, as well as to contribute to progress and improvement in medical practice and patient health care.
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