Can Open Distal Repair Be Safely Used in All Patients with Type A Acute Aortic Dissection?

Georgi Manchev, Vassil Gegouskov, Vladimir Kornovski, Georgi Yankov, Valya Goranovska, Vicktoria Ilieva, Vicktoria Petrova
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Abstract

Purpose: The distal suture line during aortic dissection repair can be performed by a closed technique or by an open technique. This study presents a retrospective comparison of both methods regarding their postoperative outcomes.

Patients and methods: 120 patients who underwent surgery for acute aortic dissection type A were divided into two groups. In group A (n = 81), open distal anastomosis was performed under hypothermic circulatory arrest and selective cerebral perfusion. In group B (n = 39), distal anastomosis was performed with the aorta cross-clamped under mildly hypothermic cardiopulmonary bypass. Primary outcomes were operative mortality, neurologic morbidity, and long-term survival.

Results: Hospital mortality (17.3% for the open group vs. 12.8% for the closed group, p = 0.53), permanent neurologic dysfunction (8.7% vs. 8.3%, p = 1.0), and temporary neurologic dysfunction (31.9% vs. 22.2%, p = 0.298) were not significantly different between groups. No significant difference in actuarial 5- and 10-year survival was observed (88% vs. 86% and 53 vs. 73%, respectively, p = 0.396). After propensity-score adjustment, the technique of distal aortic repair was not found to be a predictor of the primary outcomes.

Conclusion: We conclude that the open repair can be used in most if not all cases of surgical repair of type A acute aortic dissection.

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开放性远端修复术能安全地用于所有A型急性主动脉夹层患者吗?
目的:主动脉夹层修复过程中的远端缝合线可以通过闭合技术或开放技术进行。本研究对两种方法的术后结果进行了回顾性比较。患者和方法:将120例接受A型急性主动脉夹层手术的患者分为两组。A组(n=81)在低温停循环和选择性脑灌注下进行开放式远端吻合。B组(n=39)在轻度低温体外循环下进行远端吻合,主动脉交叉夹紧。主要结果是手术死亡率、神经系统发病率和长期生存率。结果:住院死亡率(开放组17.3%,封闭组12.8%,p=0.053)、永久性神经功能障碍(8.7%,8.3%,p=0.0)和暂时性神经功能障碍的发生率(31.9%,22.2%,p=0.0298)在各组之间没有显著差异。在5年和10年的精算生存率方面没有观察到显著差异(分别为88%对86%和53%对73%,p=0.396)。在倾向评分调整后,未发现远端主动脉修复技术是主要结果的预测因素。结论:开放式修补术可用于大多数(如果不是全部的话)A型急性主动脉夹层的外科修复。
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