3D laparoscopic salvage radical prostatectomy: mini-series report and review of the literature.

Vlad Horia Schitcu, Mira Florea, Nucu Alexandru Marica, Ioan-Catalin Vlad, Ion Cojocaru, Vlad Munteanu, Paul Kubelac, Mihnea Bogdan Borz
{"title":"3D laparoscopic salvage radical prostatectomy: mini-series report and review of the literature.","authors":"Vlad Horia Schitcu, Mira Florea, Nucu Alexandru Marica, Ioan-Catalin Vlad, Ion Cojocaru, Vlad Munteanu, Paul Kubelac, Mihnea Bogdan Borz","doi":"","DOIUrl":null,"url":null,"abstract":"<p><strong>Purpose: </strong>Salvage therapy represents a rescue therapy, given after the first line of treatment had failed.The purpose of this study was to review the outcomes of patients who underwent salvage laparoscopic radical prostatectomy (sLRP) in our department and to review current published studies.</p><p><strong>Methods: </strong>Our mini-series consisted of 6 patients with recurrent prostate cancer(PCa) after non-surgical primary treatment. All interventions were performed by a single surgeon from the Oncological Institute \"Prof. Dr. Ion Chiricuta\" Cluj Napoca, Romania.A literature review was carried out in June 2020 using the PubMed and MEDLINE databases to identify relevant studies published in the literature between 2000 and 2020. Six papers were selected for our review.We reviewed the oncological and functional outcomes of patients that underwent sLRP.</p><p><strong>Results: </strong>Extraperitoneal sLRP was performed in 6 patients. Biochemical failure after primary treatment developed between one and five years. Mean operative time was 135.5 min, mean blood loss was 328 ml. No intraoperative complications occurred and no conversions to open surgery. R0 was achieved in 5 out of the 6 patients (83.5%). Out of the 6 patients 2 are incontinent.</p><p><strong>Conclusions: </strong>SLRP remains an underused procedure and a missed therapeutic opportunity for selected patients. From published data and personal experience, we conclude that in experienced hands sLRP for localized prostate cancer is a feasible, safe and efficient method to treat recurrent PCa. Short-term oncological outcomes are optimistic but further studies need to be made to observe the long-term outcomes.</p>","PeriodicalId":94065,"journal":{"name":"Journal of B.U.ON. : official journal of the Balkan Union of Oncology","volume":"26 3","pages":"964-969"},"PeriodicalIF":0.0000,"publicationDate":"2021-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Journal of B.U.ON. : official journal of the Balkan Union of Oncology","FirstCategoryId":"1085","ListUrlMain":"","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 0

Abstract

Purpose: Salvage therapy represents a rescue therapy, given after the first line of treatment had failed.The purpose of this study was to review the outcomes of patients who underwent salvage laparoscopic radical prostatectomy (sLRP) in our department and to review current published studies.

Methods: Our mini-series consisted of 6 patients with recurrent prostate cancer(PCa) after non-surgical primary treatment. All interventions were performed by a single surgeon from the Oncological Institute "Prof. Dr. Ion Chiricuta" Cluj Napoca, Romania.A literature review was carried out in June 2020 using the PubMed and MEDLINE databases to identify relevant studies published in the literature between 2000 and 2020. Six papers were selected for our review.We reviewed the oncological and functional outcomes of patients that underwent sLRP.

Results: Extraperitoneal sLRP was performed in 6 patients. Biochemical failure after primary treatment developed between one and five years. Mean operative time was 135.5 min, mean blood loss was 328 ml. No intraoperative complications occurred and no conversions to open surgery. R0 was achieved in 5 out of the 6 patients (83.5%). Out of the 6 patients 2 are incontinent.

Conclusions: SLRP remains an underused procedure and a missed therapeutic opportunity for selected patients. From published data and personal experience, we conclude that in experienced hands sLRP for localized prostate cancer is a feasible, safe and efficient method to treat recurrent PCa. Short-term oncological outcomes are optimistic but further studies need to be made to observe the long-term outcomes.

分享 分享
微信好友 朋友圈 QQ好友 复制链接
本刊更多论文
三维腹腔镜根治性前列腺切除术:迷你系列报告和文献回顾。
目的:抢救性治疗是指在第一线治疗失败后进行的抢救性治疗。本研究的目的是回顾在我科接受挽救性腹腔镜前列腺根治术(sLRP)的患者的结果,并回顾目前已发表的研究。方法:我们的迷你系列包括6例经非手术治疗的复发性前列腺癌症(PCa)患者。所有干预措施均由罗马尼亚Cluj Napoca肿瘤研究所“Ion Chiricuta教授博士”的一名外科医生进行。2020年6月,使用PubMed和MEDLINE数据库进行了文献综述,以确定2000年至2020年间发表在文献中的相关研究。我们挑选了六篇论文进行审查。我们回顾了接受sLRP的患者的肿瘤学和功能结果。结果:6例患者行腹膜外sLRP。初次治疗后的生化衰竭发生在一到五年之间。平均手术时间为135.5分钟,平均失血量为328毫升。没有发生术中并发症,也没有转为开放手术。6例患者中有5例(83.5%)达到R0,其中2例大小便失禁。结论:对于选定的患者来说,SLRP仍然是一种未充分利用的手术,也是一种错失的治疗机会。根据已发表的数据和个人经验,我们得出结论,在经验丰富的人手中,sLRP治疗局限性前列腺癌症是一种可行、安全和有效的治疗复发性前列腺癌的方法。短期肿瘤学结果是乐观的,但需要进行进一步的研究来观察长期结果。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
求助全文
约1分钟内获得全文 去求助
来源期刊
自引率
0.00%
发文量
0
期刊最新文献
3D laparoscopic salvage radical prostatectomy: mini-series report and review of the literature. Mismatch repair status in high-grade endometrial carcinomas of endometrioid and non-endometrioid type. Inhibition of cancer cell growth in gemcitabine-resistant pancreatic carcinoma by mangiferin phytochemical involves induction of autophagy, endogenous ROS production, cell cycle disruption, mitochondrial mediated apoptosis and suppression of cancer cell migration and invasion. Role of miR-489 in the proliferation and apoptosis of pancreatic carcinoma. Ginseng and cancer.
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
现在去查看 取消
×
提示
确定
0
微信
客服QQ
Book学术公众号 扫码关注我们
反馈
×
意见反馈
请填写您的意见或建议
请填写您的手机或邮箱
已复制链接
已复制链接
快去分享给好友吧!
我知道了
×
扫码分享
扫码分享
Book学术官方微信
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术
文献互助 智能选刊 最新文献 互助须知 联系我们:info@booksci.cn
Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。
Copyright © 2023 Book学术 All rights reserved.
ghs 京公网安备 11010802042870号 京ICP备2023020795号-1