Medulloblastoma in Adulthood

D. Horșia
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引用次数: 17

Abstract

Abstract Defined as a tumour with increased malignancy potential in childhood, medulloblastoma was first reported in the literature by Percival Bailey and Harvey Cushing in 1925. Scientific studies over the years have shown that this type of tumour represents about 20% of all intracranial tumours encountered in childhood, their percentage decreasing with advancing age. The genetic factor plays an important part in the appearance of medulloblastoma; there are certain diseases, in the patient’s history, that can be associated with this type of tumour. Here, we can specify Turcot syndrome (an autosomal recessive disease, rarely encountered) or basal cell carcinoma syndrome. This article presents the case of a young patient (41-year-old) suffering from a cerebellar tumour formation that turned out to be, after histopathological examination, a medulloblastoma. In practice we can find several types of medulloblastoma (desmoplastic or nodular, anaplastic, classical or undifferentiated). In what follows I will try to highlight a few aspects of a classic medulloblastoma.
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成人期髓母细胞瘤
髓母细胞瘤是一种儿童期恶性肿瘤,由Percival Bailey和Harvey Cushing于1925年首次报道。多年来的科学研究表明,这种类型的肿瘤约占儿童时期颅内肿瘤的20%,随着年龄的增长,这一比例会下降。遗传因素在成神经管细胞瘤的发生中起重要作用;在病人的病史中,有某些疾病可能与这种肿瘤有关。在这里,我们可以指定Turcot综合征(常染色体隐性遗传病,很少遇到)或基底细胞癌综合征。这篇文章提出了一个年轻的病人(41岁)患有小脑肿瘤形成,结果是,经组织病理学检查,髓母细胞瘤。在实践中,我们可以发现几种类型的髓母细胞瘤(结缔组织增生或结节状、间变性、典型或未分化)。接下来,我将着重介绍典型髓母细胞瘤的几个方面。
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