Bioactivity of Heterotrigona itama Propolis as Anti-Inflammatory: A Review

Q3 Biochemistry, Genetics and Molecular Biology Biointerface Research in Applied Chemistry Pub Date : 2022-09-11 DOI:10.33263/briac134.326

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Abstract

Chronic inflammation is common in infectious diseases, rheumatoid arthritis, gout, and autoimmune diseases. Several pharmaceutical therapies are readily available. However, using non-steroidal anti-inflammatory drugs (NSAIDs) is accompanied by dangerous side effects. Therefore, searching for safer alternative therapies with no side effects is very important. Currently, natural sources of kelulut bee (Heterotrigona itama) propolis have not been fully utilized for treatment, especially for inflammation. This study aims to study the bioactivity of kelulut bee propolis H. itama as an anti-inflammatory. The literature review was used as a method by searching related journals using Google Scholar, PubMed, Scopus, and Garuda. Based on the study's results, it was found that H. itama propolis has the potential to suppress inflammation through the inhibition of free radicals and decrease COX-2. The compounds that have the potential to have this activity are influenced by the resin source collected by the kelulut bees. This information can be used as a reference for developing natural ingredients from propolis for anti-inflammatory properties.

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异三角蜂蜂胶抗炎生物活性研究进展

慢性炎症常见于传染病、类风湿性关节炎、痛风和自身免疫性疾病。几种药物疗法很容易获得。然而，使用非甾体抗炎药（NSAIDs）会伴随着危险的副作用。因此，寻找更安全、无副作用的替代疗法非常重要。目前，kelulut蜂蜂胶的天然来源尚未完全用于治疗，尤其是炎症。本研究旨在研究蜂蜂胶的抗炎活性。文献综述作为一种方法，使用Google Scholar、PubMed、Scopus和Garuda搜索相关期刊。根据研究结果，发现香菇蜂胶具有通过抑制自由基和降低COX-2来抑制炎症的潜力。有可能具有这种活性的化合物受到kelulut蜜蜂收集的树脂来源的影响。这些信息可作为从蜂胶中开发具有抗炎特性的天然成分的参考。

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来源期刊

Biointerface Research in Applied Chemistry CHEMISTRY, APPLIED-

CiteScore

4.80

自引率

0.00%

发文量

256

期刊介绍： Biointerface Research in Applied Chemistry is an international and interdisciplinary research journal that focuses on all aspects of nanoscience, bioscience and applied chemistry. Submissions are solicited in all topical areas, ranging from basic aspects of the science materials to practical applications of such materials. With 6 issues per year, the first one published on the 15th of February of 2011, Biointerface Research in Applied Chemistry is an open-access journal, making all research results freely available online. The aim is to publish original papers, short communications as well as review papers highlighting interdisciplinary research, the potential applications of the molecules and materials in the bio-field. Our aim is to encourage scientists to publish their experimental and theoretical results in as much detail as possible.