Analisis In Silico dan Kuantitatif Senyawa Metabolit Sekunder Senyawa L-DOPA Pada Ekstrak Biji Dan Daun Kacang Koro Benguk (Mucuna pruriens D.C.) menggunakan metode Spektrometri UV-VIS

Winda Tul Habibah, Tintrim Rahayu, M. Ramadhan
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Abstract

Koro Benguk (Mucuna pruriens D.C.) is a plant that produces medicinal ingredients containing secondary metabolites, one of which is L-DOPA. This compound can be used to treat nervous disorders, treat snake venom, increase body weight and muscle strength, and as an anthelmintic in humans. This study aims to analyze the Benguk Koro Bean (Mucuna pruriens D.C.) In Silico and detect the presence of L-DOPA compounds in the Benguk Koro Bean (Mucuna pruriens D.C.) species using UV-VIS Spectrometry. The methods used are the description method and the data processed descriptively qualitatively. The results showed that in In Silico analysis it was found that the Benguk Koro Bean (Mucuna pruriens D.C.) species in the seeds and leaves contained L-DOPA compounds and had a C9H11NO4 molecular structure, while for the detection of L-DOPA compounds using UV-VIS spectrometry it was detected that Koro Benguk Bean (Mucuna pruriens D.C.) contains L-DOPA with a wavelength of 462 nm with absorbance in seeds and leaves of 2,210 and 1,171, respectively. The conclusion of this study is that with 20 grams of koro benguk seeds it produces 1.105 ppm, while for 2 grams of koro benguk leaves it produces 0.5855 ppm.
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利用UV-VIS光谱分析方法对硅胶和定量的二分半代谢化合物的草本植物提取物(Mucuna pruriens D.C)进行分析
Koro Benguk(Mucuna瘙痒症D.C.)是一种产生含有次级代谢产物的药用成分的植物,其中一种是L-DOPA。这种化合物可用于治疗神经系统疾病、治疗蛇毒、增加体重和肌肉力量,并可作为人类的驱虫剂。本研究旨在分析Silico中的Benguk Koro Bean(Mucuna瘙痒症D.C.),并使用UV-VIS光谱法检测Benguk科罗Bean(Mucura瘙痒症D.)物种中L-DOPA化合物的存在。所使用的方法是描述方法和定性描述处理的数据。结果表明,在in Silico分析中发现,种子和叶片中的Benguk Koro Bean(Mucuna pulcens D.C.)物种含有L-DOPA化合物并具有C9H11NO4分子结构,而对于使用UV-VIS光谱法检测L-DOPA化合物,检测到Koro Benguk Bean(Mucuna瘙痒症D.C.)含有波长为462nm的L-DOPA,在种子和叶片中的吸光度分别为2210和1171。这项研究的结论是,20克科罗本古克种子的产量为1.105 ppm,而2克科罗本古克叶片的产量为0.5855 ppm。
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