The Origin of Pilonidal Sinus Disease – 10 wrong Theories and one Recent Discovery

M. Dettmer, K. Degiannis, Myriam Braun-Münker, D. Doll, M. Maak
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Abstract

Introduction: In the last two centuries, many theories have been proposed to explain the origin of pilonidal sinus disease (PSD) – congenital and acquired. Materials and Methods: A PubMed literature review was conducted and looked at different proposed theories on the origin of PSD; this overview was then compared to research results from more recent studies. Results: Initially it was postulated, that PSD was of embryonic origin. This however changed during World War II as more 78.000 American soldiers were diagnosed and treated for PSD. Thereafter, the perception of the origin of PSD changed to an acquired one. New data has shown that short hair fragments, which have fallen from the scalp may be the origin of PSD – therefore disproving the theory of folliculitis and fatty gland obstruction. Conclusion: These new findings may explain why recurrences/new diseases occur within follicle-free areas – such as scars and without any preceding infection. This may aid in the prevention of PSD.  
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毛窦疾病的起源- 10个错误的理论和一个最近的发现
在过去的两个世纪里,许多理论被提出来解释毛毛窦疾病(PSD)的起源-先天性和后天性。材料和方法:对PubMed文献进行了回顾,并研究了关于PSD起源的不同理论;然后将这一概述与最近的研究结果进行比较。结果:初步推测PSD起源于胚胎。然而,这种情况在第二次世界大战期间发生了变化,超过78000名美国士兵被诊断和治疗为ptsd。此后,对PSD起源的认识转变为后天的认识。新的数据表明,从头皮上脱落的短头发碎片可能是PSD的起源,因此反驳了毛囊炎和脂肪腺阻塞的理论。结论:这些新发现可以解释为什么复发/新的疾病发生在无卵泡区域-如疤痕和没有任何先前的感染。这可能有助于预防PSD。
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