{"title":"BIOLOGICAL ACTIVITIES AND CHEMICAL COMPOSITION OF Rubia tinctorum (L) ROOT AND AERIAL PART EXTRACTS THEREOF.","authors":"Fatima Zohra Houari, R. Erenler, A. Hariri","doi":"10.15446/abc.v27n3.95476","DOIUrl":null,"url":null,"abstract":"In the present study, the phytochemical composition, antioxidant and anti-hemolytic activities of root and aerial part Rubia tinctorum hydromethanolic extracts were investigated. Phytochemical screening reveals the presence of phenol, alkaloids, coumarin, flavonoids, and tannins in both extracts. LC-ESI-MS/MS analysis showed the presence of 15 and 17 components in the root and the aerial part extracts, respectively. The quantitative analysis indicates the richness of root extracts in phenolic compounds (118.38 mg GAE/g) and flavonoids (45.29±0.04 mg GAE/g), the aerial part extract has the highest levels in tannins (134.1±0.1 mg GAE/g). Besides, aerial part extracts revealed the highest antioxidant activity for DPPH (83.23 %) and FRAP (1.51±0.22), while the root extract exhibited the highest potential for TAC and antihemolytic activity (61.09 %). Rubia tinctorum contains different active compounds to prevent diseases related to oxidative stress.","PeriodicalId":56052,"journal":{"name":"Acta Biologica Colombiana","volume":"1 1","pages":""},"PeriodicalIF":0.5000,"publicationDate":"2022-03-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"4","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Acta Biologica Colombiana","FirstCategoryId":"99","ListUrlMain":"https://doi.org/10.15446/abc.v27n3.95476","RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q4","JCRName":"PLANT SCIENCES","Score":null,"Total":0}
引用次数: 4
Abstract
In the present study, the phytochemical composition, antioxidant and anti-hemolytic activities of root and aerial part Rubia tinctorum hydromethanolic extracts were investigated. Phytochemical screening reveals the presence of phenol, alkaloids, coumarin, flavonoids, and tannins in both extracts. LC-ESI-MS/MS analysis showed the presence of 15 and 17 components in the root and the aerial part extracts, respectively. The quantitative analysis indicates the richness of root extracts in phenolic compounds (118.38 mg GAE/g) and flavonoids (45.29±0.04 mg GAE/g), the aerial part extract has the highest levels in tannins (134.1±0.1 mg GAE/g). Besides, aerial part extracts revealed the highest antioxidant activity for DPPH (83.23 %) and FRAP (1.51±0.22), while the root extract exhibited the highest potential for TAC and antihemolytic activity (61.09 %). Rubia tinctorum contains different active compounds to prevent diseases related to oxidative stress.
Acta Biologica ColombianaAgricultural and Biological Sciences-General Agricultural and Biological Sciences
CiteScore
1.60
自引率
0.00%
发文量
21
审稿时长
13 weeks
期刊介绍：
The journal is published quarterly and divulges original and unpublished results of basic and applied research about biological subjects with special interest in Neotropical region. Manuscripts may be research articles, reviews, reflection articles or short notes. The Acta biol. Colomb Journal have a scientific and editorial board composed of expert researchers of in their areas of knowledge.
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