Alopecia Areata and it’s Association with Thyroid Dysfunction

A. Rai, Rajeev Yadav, S. Karki, M. Pradhan
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引用次数: 1

Abstract

Background: Out of many cause of non-scarring alopecia, alopecia areata is one the cause of non-scarring alopecia. Most study till now has shown autoimmunity to be pathogenesis of alopecia areata and has found to be frequently associated with abnormal thyroid function. The current study aims to early detection of thyroid dysfunction in AA patient and reduce morbidity related to thyroid disorder. Materials and Methods: This was a prospective observational study conducted over a period of 1 year from July 2018 to June 2019 in department of dermatology Nobel Medical College, Biratnagar. Any patient who presented with clinical features of alopecia areata were included in the study. Results: In our study, only 5 (7.1%) patients showed abnormal thyroid function tests, and other 65 (92.9%) had normal thyroid function. 3 patients (4.3%) had hypothyroidism and 2 patients (2.9%) had hyperthyroidism. In those presenting with thyroid dysfunction, 3 (10.3%) were females and 2 (4.9%) were males Mean age of onset of alopecia areata was 27.8 years. Conclusion: Our study did not show significant association of alopecia areata with thyroid dysfunction. However this study showed male preponderance in alopecia areata though thyroid dysfunction was seen more in female.
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斑秃及其与甲状腺功能障碍的关系
背景:在非瘢痕性脱发的多种病因中,斑秃是非瘢痕性秃发的病因之一。迄今为止,大多数研究表明自身免疫是斑秃的发病机制,并发现其经常与甲状腺功能异常有关。目前的研究旨在早期发现AA患者的甲状腺功能障碍,并降低与甲状腺疾病相关的发病率。材料和方法:这是一项前瞻性观察性研究,于2018年7月至2019年6月在比拉特纳加诺贝尔医学院皮肤科进行,为期1年。任何表现出斑秃临床特征的患者都被纳入研究。结果:在我们的研究中,只有5名(7.1%)患者的甲状腺功能测试异常,其他65名(92.9%)的甲状腺功能正常。甲状腺功能减退3例(4.3%),甲状腺功能亢进2例(2.9%)。在甲状腺功能障碍的患者中,3名(10.3%)为女性,2名(4.9%)为男性。斑秃的平均发病年龄为27.8岁。结论:我们的研究没有显示斑秃与甲状腺功能紊乱有显著的相关性。然而,这项研究表明,男性在斑秃中占优势,尽管女性甲状腺功能障碍更常见。
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19
审稿时长
16 weeks
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