首页 > 最新文献

Journal of Nobel Medical College最新文献

英文 中文
Port Site Infection after Elective Laparoscopic Cholecystectomy with or without the Use of Prophylactic Antibiotics: A Comparative Cross-Sectional Study 选择性腹腔镜胆囊切除术后端口感染的横断面比较研究
Pub Date : 2023-07-17 DOI: 10.3126/jonmc.v12i1.56496
Y. Shakya, Samjhana Basnet, Latika Giri, Ajay K.C., R. Karmacharya
Background: Laparoscopic surgery, a minimally invasive procedure, has gained popularity due to early recovery rate and minimal incision. Port site infection following laparoscopic surgery is an infrequent complication, increasing patient's morbidity, and also damaging surgeon's reputation. It depends on sterilization and surgical techniques, which have improved with time. The aim of this study is to evaluate the role of prophylactic antibiotics in preventing port site infection after laparoscopic cholecystectomy. Materials and Methods: A comparative cross-sectional study on 200 patients undergoing elective laparoscopic cholecystectomy was conducted from November 2021 to February 2022 in tertiary care Hospital by using systematic random sampling.Among the 200 patients, 100 odd numbered patients were given antibiotics, and 100 even numbered patients were not. The outcome of the two groups was measured with regard to port site infection. Results: The mean age in prophylactic antibiotic receiving group and not receiving group was 42.13 (SD = 14.41) and 42.71(SD = 14.29) years, respectively. The female: male ratio for total patients was 2.77.There were three cases of port site infection in total, in group receiving antibiotics (Cefotaxime), there was one case, whereas in placebo group, there were two. Simple logistic regression was utilized to compare the results of two groups (p>0.05). Similarly, Chi-square test was applied to histopathology diagnosis, which showed no statistically significant difference (χ2 = 0.99, P = 0.80). Conclusion: Antibiotic prophylaxis does not lower the rate of infectious in patients undergoing elective laparoscopic cholecystectomy.
背景:腹腔镜手术是一种微创手术,由于恢复率高、切口小而广受欢迎。腹腔镜手术后端口感染是一种罕见的并发症,增加了患者的发病率,也损害了外科医生的声誉。这取决于绝育和手术技术,这些技术随着时间的推移而有所改进。本研究的目的是评估预防性抗生素在预防腹腔镜胆囊切除术后端口部位感染中的作用。材料和方法:采用系统随机抽样方法,对2021年11月至2022年2月在三级护理医院接受选择性腹腔镜胆囊切除术的200名患者进行了横断面比较研究。在200名患者中,100名奇数患者服用了抗生素,100名偶数患者没有服用。两组的结果是根据端口感染进行测量的。结果:预防性使用抗生素组和不使用抗生素组的平均年龄分别为42.13(SD=14.41)和42.71(SD=14.29)岁。总患者的女性与男性比例为2.77。共有3例端口部位感染,接受抗生素(头孢噻肟)治疗的组有1例,而安慰剂组有2例。采用简单逻辑回归分析比较两组的结果(p>0.05),组织病理学诊断采用卡方检验,差异无统计学意义(χ2=0.99,p=0.80)。
{"title":"Port Site Infection after Elective Laparoscopic Cholecystectomy with or without the Use of Prophylactic Antibiotics: A Comparative Cross-Sectional Study","authors":"Y. Shakya, Samjhana Basnet, Latika Giri, Ajay K.C., R. Karmacharya","doi":"10.3126/jonmc.v12i1.56496","DOIUrl":"https://doi.org/10.3126/jonmc.v12i1.56496","url":null,"abstract":"Background: Laparoscopic surgery, a minimally invasive procedure, has gained popularity due to early recovery rate and minimal incision. Port site infection following laparoscopic surgery is an infrequent complication, increasing patient's morbidity, and also damaging surgeon's reputation. It depends on sterilization and surgical techniques, which have improved with time. The aim of this study is to evaluate the role of prophylactic antibiotics in preventing port site infection after laparoscopic cholecystectomy. \u0000Materials and Methods: A comparative cross-sectional study on 200 patients undergoing elective laparoscopic cholecystectomy was conducted from November 2021 to February 2022 in tertiary care Hospital by using systematic random sampling.Among the 200 patients, 100 odd numbered patients were given antibiotics, and 100 even numbered patients were not. The outcome of the two groups was measured with regard to port site infection. \u0000Results: The mean age in prophylactic antibiotic receiving group and not receiving group was 42.13 (SD = 14.41) and 42.71(SD = 14.29) years, respectively. The female: male ratio for total patients was 2.77.There were three cases of port site infection in total, in group receiving antibiotics (Cefotaxime), there was one case, whereas in placebo group, there were two. Simple logistic regression was utilized to compare the results of two groups (p>0.05). Similarly, Chi-square test was applied to histopathology diagnosis, which showed no statistically significant difference (χ2 = 0.99, P = 0.80). \u0000Conclusion: Antibiotic prophylaxis does not lower the rate of infectious in patients undergoing elective laparoscopic cholecystectomy.","PeriodicalId":52824,"journal":{"name":"Journal of Nobel Medical College","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-07-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47125561","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Clinico-Epidemiological Profile and Outcome of Poisoning in Children Presenting at a Tertiary Care Hospital of Eastern Nepal 尼泊尔东部三级医院儿童中毒的临床流行病学概况和结果
Pub Date : 2023-07-17 DOI: 10.3126/jonmc.v12i1.56282
A. Giri, V. Sah, S. Yadav, Niraj S. Yadav
Background: Pediatric poisoning is common emergency worldwide and represents major and preventable cause of morbidity and mortality in children. The study describes epidemiology and outcome of acute poisonings in children presenting to Nobel Medical College through Emergency and Outpatient department and determines causative agents and characteristics of acute poisoning in several pediatric age groups. Material and Methods: This was hospital based prospective cross-sectional study which included all acutely poisoned patients under 18yrs age of either sex who presented to Nobel Medical College Teaching Hospital during 1year period (January 2021 to December 2021). Various socio-demographic variables, poisoning details, clinical manifestations, treatment given, outcome and complications were entered in predesigned proforma. Data was entered in excel sheet and descriptive analysis was done using SPSS software (version 20). Results: During the study period total 56 children with poisoning were admitted and enrolled.  The mean age (±SD) of children with poisoning was 8.18 ± 5.50 Years. Poisoning cases werepredominant in male children (n=56, 53.6%). The most common poison wasorganophosphates(OP) compounds (41.1%). More than three-fourth of cases (92.9%) were symptomatic where nausea/vomiting (78.6%) was most common clinical symptoms, About 83.9% children survived, 10.7% expired and 5.4% left against medical advice (LAMA). Complications were seen in about 37.5% where shock was most common complications Conclusion: Poisoning was common in adolescent age group.Overall nature of poisoning was accidental however, in adolescent age group majority of them were suicidal in nature.Organophosphates (OP) compounds was most common type of poisoning
背景:儿童中毒是世界范围内常见的紧急情况,是儿童发病和死亡的主要和可预防的原因。本研究描述了诺贝尔医学院急诊科和门诊部儿童急性中毒的流行病学和结果,并确定了几个儿科年龄组急性中毒的病因和特征。材料和方法:这是一项基于医院的前瞻性横断面研究,纳入了诺贝尔医学院教学医院1年内(2021年1月至2021年12月)所有18岁以下急性中毒患者。各种社会人口变量、中毒细节、临床表现、给予的治疗、结果和并发症以预先设计的形式输入。数据以excel表格录入,使用SPSS软件(version 20)进行描述性分析。结果:研究期间共收治入组56例中毒患儿。中毒儿童平均年龄(±SD)为8.18±5.50岁。中毒病例以男童为主(n=56, 53.6%)。最常见的毒物是有机磷化合物(OP)(41.1%)。超过四分之三(92.9%)的病例有症状,其中恶心/呕吐(78.6%)为最常见的临床症状,约83.9%的儿童存活,10.7%的儿童死亡,5.4%的儿童不遵医嘱离开(LAMA)。并发症占37.5%,其中休克是最常见的并发症。中毒的总体性质是意外的,但在青少年年龄组中,大多数是自杀性质的。有机磷(OP)化合物是最常见的中毒类型
{"title":"Clinico-Epidemiological Profile and Outcome of Poisoning in Children Presenting at a Tertiary Care Hospital of Eastern Nepal","authors":"A. Giri, V. Sah, S. Yadav, Niraj S. Yadav","doi":"10.3126/jonmc.v12i1.56282","DOIUrl":"https://doi.org/10.3126/jonmc.v12i1.56282","url":null,"abstract":"Background: Pediatric poisoning is common emergency worldwide and represents major and preventable cause of morbidity and mortality in children. The study describes epidemiology and outcome of acute poisonings in children presenting to Nobel Medical College through Emergency and Outpatient department and determines causative agents and characteristics of acute poisoning in several pediatric age groups. \u0000Material and Methods: This was hospital based prospective cross-sectional study which included all acutely poisoned patients under 18yrs age of either sex who presented to Nobel Medical College Teaching Hospital during 1year period (January 2021 to December 2021). Various socio-demographic variables, poisoning details, clinical manifestations, treatment given, outcome and complications were entered in predesigned proforma. Data was entered in excel sheet and descriptive analysis was done using SPSS software (version 20). \u0000Results: During the study period total 56 children with poisoning were admitted and enrolled.  The mean age (±SD) of children with poisoning was 8.18 ± 5.50 Years. Poisoning cases werepredominant in male children (n=56, 53.6%). The most common poison wasorganophosphates(OP) compounds (41.1%). More than three-fourth of cases (92.9%) were symptomatic where nausea/vomiting (78.6%) was most common clinical symptoms, About 83.9% children survived, 10.7% expired and 5.4% left against medical advice (LAMA). Complications were seen in about 37.5% where shock was most common complications \u0000Conclusion: Poisoning was common in adolescent age group.Overall nature of poisoning was accidental however, in adolescent age group majority of them were suicidal in nature.Organophosphates (OP) compounds was most common type of poisoning","PeriodicalId":52824,"journal":{"name":"Journal of Nobel Medical College","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-07-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44301404","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Prevalence and Antibiogram of Bacterial Uropathogens from a Tertiary Care Hospital of Eastern Nepal 尼泊尔东部某三级医院尿路细菌病原菌的流行及抗生素谱分析
Pub Date : 2023-07-17 DOI: 10.3126/jonmc.v12i1.56340
K. Shrestha, P. Singh, K. R. Yadav, G. Singh
Background: Urinary tract infection (UTI) is defined as growth of micro-organisms >105 CFU/ml in mid-stream urine samples. [1] Globally, urinary tract infection is considered a major public health concern with the second most common bacterial infection affecting individuals of different ages. It is estimated that worldwide 150 million cases of UTI occur per year and bacteria are responsible for about 95% of all the cases with each year. [3, 4] This study was designed to describe the pattern of microorganisms causing UTI and their antibiotic sensitivity. Materials and Methods: This is a hospital based cross-sectional study conducted in the Department of Microbiology from January 2022 to June 2022 after taking ethical approval from Institutional Review Committee, Nobel Medical College and Teaching Hospital, Biratnagar, Nepal. The patient profiles or records visiting a tertiary care hospital of both sex and every age group who were having symptoms and clinical diagnosis of urinary tract infection were included. Results: A total of 2247 urine samples were collected, 501(22.29%) of the urine sample yielded significant growth of uropathogenes. The most common bacteria was found to be Escherichia coli (E. coli) that accounts for 73.05% followed by Enterococcus species 11.57%, Klebsiella pneumoniae 8.98% and amikacin and nitrofurantoin was found to be the most sensitive antibiotic to gram negative uropathogens. Conclusion: The prevalence of uropathogenes was found to be higher in our study. Significant bacteriuria was seen in the female than male. The total number of patient with culture positivity was higher in younger age groups with high frequency of antibiotic resistance
背景:尿路感染(UTI)是指中期尿液样本中大于105CFU/ml的微生物生长。[1] 在全球范围内,尿路感染被认为是一个主要的公共卫生问题,是影响不同年龄段人群的第二常见细菌感染。据估计,全球每年发生1.5亿例尿路感染病例,细菌约占每年所有病例的95%。[3,4]本研究旨在描述引起尿路感染的微生物模式及其抗生素敏感性。材料和方法:这是一项基于医院的横断面研究,于2022年1月至2022年6月在获得尼泊尔比拉特纳格尔诺贝尔医学院和教学医院机构审查委员会的伦理批准后,在微生物系进行。包括有尿路感染症状和临床诊断的性别和每个年龄组的三级护理医院就诊的患者档案或记录。结果:共采集了2247份尿液样本,其中501份(22.29%)的尿液样本产生了显著的泌尿系生长。最常见的细菌是大肠杆菌(E.coli),占73.05%,其次是肠球菌11.57%,肺炎克雷伯菌8.98%,阿米卡星和呋喃妥因是对革兰氏阴性尿路病原体最敏感的抗生素。结论:在我们的研究中发现泌尿系致病基因的患病率较高。女性明显多于男性。在抗生素耐药性高的年轻群体中,培养阳性患者的总数更高
{"title":"Prevalence and Antibiogram of Bacterial Uropathogens from a Tertiary Care Hospital of Eastern Nepal","authors":"K. Shrestha, P. Singh, K. R. Yadav, G. Singh","doi":"10.3126/jonmc.v12i1.56340","DOIUrl":"https://doi.org/10.3126/jonmc.v12i1.56340","url":null,"abstract":"Background: Urinary tract infection (UTI) is defined as growth of micro-organisms >105 CFU/ml in mid-stream urine samples. [1] Globally, urinary tract infection is considered a major public health concern with the second most common bacterial infection affecting individuals of different ages. It is estimated that worldwide 150 million cases of UTI occur per year and bacteria are responsible for about 95% of all the cases with each year. [3, 4] This study was designed to describe the pattern of microorganisms causing UTI and their antibiotic sensitivity. \u0000Materials and Methods: This is a hospital based cross-sectional study conducted in the Department of Microbiology from January 2022 to June 2022 after taking ethical approval from Institutional Review Committee, Nobel Medical College and Teaching Hospital, Biratnagar, Nepal. The patient profiles or records visiting a tertiary care hospital of both sex and every age group who were having symptoms and clinical diagnosis of urinary tract infection were included. \u0000Results: A total of 2247 urine samples were collected, 501(22.29%) of the urine sample yielded significant growth of uropathogenes. The most common bacteria was found to be Escherichia coli (E. coli) that accounts for 73.05% followed by Enterococcus species 11.57%, Klebsiella pneumoniae 8.98% and amikacin and nitrofurantoin was found to be the most sensitive antibiotic to gram negative uropathogens. \u0000Conclusion: The prevalence of uropathogenes was found to be higher in our study. Significant bacteriuria was seen in the female than male. The total number of patient with culture positivity was higher in younger age groups with high frequency of antibiotic resistance","PeriodicalId":52824,"journal":{"name":"Journal of Nobel Medical College","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-07-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44218656","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Pattern of Drug Prescription in Patients with Chronic Kidney Disease Maintained on Hemodialysis in a Tertiary Care Hospital 某三级医院血液透析维持慢性肾病患者的用药模式
Pub Date : 2023-07-17 DOI: 10.3126/jonmc.v12i1.56263
N. K. Yadav, K. Kandel, R. Ghimire
Background: Chronic kidney disease affects the structure and function of the kidneys over a specific period of time. It is a worldwide public health related problem. It is usually associated with increasing age, hypertension, diabetes, cardiovascular disease and lack of exercise. Materials and Methods: It was a cross-sectional observational study conducted at Nobel Medical College Teaching Hospital. A total 150 patients were enrolled in this study from March 2021 to February 2022. Patients aged 18 years and above diagnosed with chronic kidney disease and treated with dialysis were included in this study. Statistical tools were used to describe the relevant data. Results: Chronic kidney disease was more predominant among males 90 (60%) than females 60 (40%). Thecommon co-morbid conditions were hypertension 51(34%) followed by hypertension & diabetes 40 (26.66%). 115 (76.66%) patients were receivinghemodialysis twice followed by 26 (17.33%) who were receiving it thrice a week. An average of 7.03 drugs per prescription was advised. Commonly used drugs were hydrocortisone 145 (96.66%), torsemide 90 (85.71%), and vitamin D3 105 (75%). Among the complications, the most commonly occurred were chills & rigor 15 (10%) followed by backache 12 (8%). Conclusion: Hydrocortisone, torsemide and Vit.D3, were prescribed medications in CKD patients maintained on hemodialysis. Hydrocortisone was commonly used at this tertiary care hospital. Chills & rigor and backache were complication occurred during hemodialysis.
背景:慢性肾脏疾病会在一段特定的时间内影响肾脏的结构和功能。这是一个全球性的公共卫生问题。它通常与年龄增长、高血压、糖尿病、心血管疾病和缺乏运动有关。材料和方法:这是一项在诺贝尔医学院教学医院进行的横断面观察性研究。从2021年3月到2022年2月,共有150名患者参与了这项研究。本研究纳入了18岁及以上被诊断为慢性肾脏疾病并接受透析治疗的患者。统计工具被用来描述相关数据。结果:男性慢性肾脏疾病90例(60%),女性60例(40%)。常见的合并疾病是高血压51例(34%),其次是高血压和糖尿病40例(26.66%)。115例(76.66%)患者接受了两次血液透析,26例(17.33%)患者每周接受三次血液透析。建议每个处方平均服用7.03种药物。常用药物有氢化可的松145(96.66%)、托塞米90(85.71%)和维生素D3 105(75%)。在并发症中,最常见的是发冷和僵硬15例(10%),其次是背痛12例(8%)。结论:氢化可的松、托塞米和维生素D3是维持血液透析的CKD患者的处方药。氢化可的松在这家三级医院很常用。血液透析过程中出现寒战、腰酸背痛等并发症。
{"title":"Pattern of Drug Prescription in Patients with Chronic Kidney Disease Maintained on Hemodialysis in a Tertiary Care Hospital","authors":"N. K. Yadav, K. Kandel, R. Ghimire","doi":"10.3126/jonmc.v12i1.56263","DOIUrl":"https://doi.org/10.3126/jonmc.v12i1.56263","url":null,"abstract":"Background: Chronic kidney disease affects the structure and function of the kidneys over a specific period of time. It is a worldwide public health related problem. It is usually associated with increasing age, hypertension, diabetes, cardiovascular disease and lack of exercise. \u0000Materials and Methods: It was a cross-sectional observational study conducted at Nobel Medical College Teaching Hospital. A total 150 patients were enrolled in this study from March 2021 to February 2022. Patients aged 18 years and above diagnosed with chronic kidney disease and treated with dialysis were included in this study. Statistical tools were used to describe the relevant data. \u0000Results: Chronic kidney disease was more predominant among males 90 (60%) than females 60 (40%). Thecommon co-morbid conditions were hypertension 51(34%) followed by hypertension & diabetes 40 (26.66%). 115 (76.66%) patients were receivinghemodialysis twice followed by 26 (17.33%) who were receiving it thrice a week. An average of 7.03 drugs per prescription was advised. Commonly used drugs were hydrocortisone 145 (96.66%), torsemide 90 (85.71%), and vitamin D3 105 (75%). Among the complications, the most commonly occurred were chills & rigor 15 (10%) followed by backache 12 (8%). \u0000Conclusion: Hydrocortisone, torsemide and Vit.D3, were prescribed medications in CKD patients maintained on hemodialysis. Hydrocortisone was commonly used at this tertiary care hospital. Chills & rigor and backache were complication occurred during hemodialysis.","PeriodicalId":52824,"journal":{"name":"Journal of Nobel Medical College","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-07-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48322891","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Analysis of Neonatal Admission Patterns and Clinical Profiles in a Tertiary Care Center: Focus on Neonates Transferred from the Delivery Room to the Neonatal Intensive Care Unit 三级护理中心新生儿入院模式和临床特征分析——以从产房转入新生儿重症监护室的新生儿为重点
Pub Date : 2023-07-17 DOI: 10.3126/jonmc.v12i1.56390
B. Khanal, Sunilkumar. Yadav, S. Pokhrel, S. Singh, G. Baral, P. Kafle
Background: Neonatal mortality rate is very high in developing countries despite of advancement in perinatal and neonatal care with reduced neonatal mortality rate in many developed countries. This study aims to identify the reasons of admitting neonates for intensive care after vaginal delivery and their outcome. Materials and Methods: This is an observational descriptive study conducted for over a year at Nobel Medical College Teaching Hospital which included newborns delivered vaginally within the hospital. Demographic data of newborn and mother was obtained, birth weight, reason for admission and final outcome were documented. Outcomes were classified as improved with recovery, mortality and discharge on request prior to recovery. Descriptive statistics such as mean, percentage and standard deviation were obtained. Results: Total 117 neonates were admitted to intensive care out of 3452 vaginal deliveries with male to female ratio of 1.9:2. There were 60 (51.3%) preterm, 55 (47%) full term and 2 (1.7%) post term; and 68 (58.1%) were low birth weight. Prematurity with respiratory distress syndrome was the most common cause of admission (34.2%) along with birth asphyxia (29, 24.8%) and meconium aspiration syndrome (20, 17.1%). Positive Airway Pressure was required in 42 (35.9%). Blood Culture positive growth was seen in 17.9% with most common organism being Staphylococcus aureus. Mean stay was 3.75±2.49 days andmortality in the study population was 6.8%. Conclusion: Prematurity with respiratory distress syndrome, birth asphyxia and meconium aspiration syndrome were major indications for admission of newborns delivered via vaginal deliveries to neonatal intensive care unit. One-fourth required mechanical ventilation.
背景:尽管许多发达国家在围产期和新生儿护理方面取得了进步,新生儿死亡率有所下降,但发展中国家的新生儿死亡率仍然很高。本研究旨在确定阴道分娩后新生儿接受重症监护的原因及其结果。材料和方法:这是一项在诺贝尔医学院教学医院进行了一年多的观察性描述性研究,包括在医院内阴道分娩的新生儿。获得新生儿和母亲的人口学数据,记录出生体重、入院原因和最终结果。结果被分类为随着康复、死亡率和康复前要求出院而改善。获得了平均值、百分比和标准差等描述性统计数据。结果:3452例阴道分娩中,共有117例新生儿接受重症监护,男女比例为1.9:2。早产60例(51.3%),足月55例(47%),足月后2例(1.7%);68例(58.1%)为低出生体重儿。早产伴呼吸窘迫综合征是最常见的入院原因(34.2%),还有出生窒息(29.24.8%)和胎粪吸入综合征(20.17.1%)。42例(35.9%)需要气道正压。17.9%的血培养阳性生长,最常见的生物是金黄色葡萄球菌。研究人群的平均住院时间为3.75±2.49天,死亡率为6.8%。结论:早产伴呼吸窘迫综合征、出生窒息和胎粪吸入综合征是阴道分娩新生儿进入新生儿重症监护室的主要指征。四分之一需要机械通风。
{"title":"Analysis of Neonatal Admission Patterns and Clinical Profiles in a Tertiary Care Center: Focus on Neonates Transferred from the Delivery Room to the Neonatal Intensive Care Unit","authors":"B. Khanal, Sunilkumar. Yadav, S. Pokhrel, S. Singh, G. Baral, P. Kafle","doi":"10.3126/jonmc.v12i1.56390","DOIUrl":"https://doi.org/10.3126/jonmc.v12i1.56390","url":null,"abstract":"Background: Neonatal mortality rate is very high in developing countries despite of advancement in perinatal and neonatal care with reduced neonatal mortality rate in many developed countries. This study aims to identify the reasons of admitting neonates for intensive care after vaginal delivery and their outcome. \u0000Materials and Methods: This is an observational descriptive study conducted for over a year at Nobel Medical College Teaching Hospital which included newborns delivered vaginally within the hospital. Demographic data of newborn and mother was obtained, birth weight, reason for admission and final outcome were documented. Outcomes were classified as improved with recovery, mortality and discharge on request prior to recovery. Descriptive statistics such as mean, percentage and standard deviation were obtained. \u0000Results: Total 117 neonates were admitted to intensive care out of 3452 vaginal deliveries with male to female ratio of 1.9:2. There were 60 (51.3%) preterm, 55 (47%) full term and 2 (1.7%) post term; and 68 (58.1%) were low birth weight. Prematurity with respiratory distress syndrome was the most common cause of admission (34.2%) along with birth asphyxia (29, 24.8%) and meconium aspiration syndrome (20, 17.1%). Positive Airway Pressure was required in 42 (35.9%). Blood Culture positive growth was seen in 17.9% with most common organism being Staphylococcus aureus. Mean stay was 3.75±2.49 days andmortality in the study population was 6.8%. \u0000Conclusion: Prematurity with respiratory distress syndrome, birth asphyxia and meconium aspiration syndrome were major indications for admission of newborns delivered via vaginal deliveries to neonatal intensive care unit. One-fourth required mechanical ventilation.","PeriodicalId":52824,"journal":{"name":"Journal of Nobel Medical College","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-07-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47641342","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Asymptomatic Diabetes Insipidus Detected after Partial Pneumonectomy of Upper Left Lobe of Lung Diagnosed with Adenocarcinoma: An Unusual Case Report 腺癌诊断为肺左上叶部分切除术后无症状糖尿病血脂异常一例报告
Pub Date : 2023-07-17 DOI: 10.3126/jonmc.v12i1.56524
Dan Singh Budal, R. Bhatt, Chen Ling, C. Jing, Chunwei Ma, Xujun Ye
We present a case of 80 years woman chronic smoker (10 cigarettes)/ per day for 50 years diagnosed with adenocarcinoma in the upper left lobe of her lungs in a geriatric clinic. She has no history of diabetes but taking medicine for hypertension and dyslipidemia. She was admitted and operated on for partial pneumonectomy and discharged after 11 days of care with all essential drugs, and instructions. After 4 weeks of treatment, she complained of unusual polyuria, diagnosed in the department of Geriatrics, Zhongnan Hospital of Wuhan University, China.
我们报告一位80岁的女性慢性吸烟者(每天10支烟)50年,在老年诊所被诊断为肺左上叶腺癌。无糖尿病史,有高血压和血脂异常的药物。患者入院并接受部分全肺切除术手术,在接受所有基本药物治疗和指导治疗11天后出院。治疗4周后,患者在中国武汉大学中南医院老年科诊断为异常多尿。
{"title":"Asymptomatic Diabetes Insipidus Detected after Partial Pneumonectomy of Upper Left Lobe of Lung Diagnosed with Adenocarcinoma: An Unusual Case Report","authors":"Dan Singh Budal, R. Bhatt, Chen Ling, C. Jing, Chunwei Ma, Xujun Ye","doi":"10.3126/jonmc.v12i1.56524","DOIUrl":"https://doi.org/10.3126/jonmc.v12i1.56524","url":null,"abstract":"We present a case of 80 years woman chronic smoker (10 cigarettes)/ per day for 50 years diagnosed with adenocarcinoma in the upper left lobe of her lungs in a geriatric clinic. She has no history of diabetes but taking medicine for hypertension and dyslipidemia. She was admitted and operated on for partial pneumonectomy and discharged after 11 days of care with all essential drugs, and instructions. After 4 weeks of treatment, she complained of unusual polyuria, diagnosed in the department of Geriatrics, Zhongnan Hospital of Wuhan University, China.","PeriodicalId":52824,"journal":{"name":"Journal of Nobel Medical College","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-07-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47659340","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Quality of Life among Patients with Cardiovascular Diseases at Birat Medical College Teaching Hospital Birat医学院附属医院心血管疾病患者的生活质量
Pub Date : 2023-07-17 DOI: 10.3126/jonmc.v12i1.56345
Madhab Bista, S. Parajuli, R. K. Mehta, P. Shah, Raju Jayshwal, Sinet Pokharel, Himal Pandey
Background: Modern healthcare delivery needs to take care of the quality of life of patients. The burden of cardiovascular disease is increasing each year affecting the quality of life. So, we aimed to examine the quality of life of patients with cardiovascular diseases (CVD) at Birat Medical College Teaching Hospital. Materials and Methods: A hospital based cross sectional study was conducted among cardiovascular disease patients at Birat Medical College Teaching Hospital from 2023 Jan 27 to 2023 March 27.  Ethical clearance was taken from the institutional review committee. The collected data was entered in Microsoft Excel 2019 and analyzed by IBM SPSS statistics 2025. Results: Among 256 patients, the majority 67(26.2%) were in the age of 61-70 years and male 156(60.9%). Majority 91(35.5%) had coronary artery diseases. The quality of life domains ranging from least  to most  affected were  bodily pain (81.04±26.02), mental health (76.4±15.18), social functioning (68.1±24.2), role limitation due to emotional problems (67.9±43.56), physical functioning (59.02± 28.9), vitality (53.67±15.45), general perception of health (50.19±15.7) and role limitation due to physical health (46.39± 44).    Conclusion: Patients with cardiovascular disease had their quality of life affected based on their physical health, general perception of health, energy and vitality, physical functioning, role limitation due to emotional problems, social functioning, mental health and bodily pain
背景:现代医疗服务需要照顾患者的生活质量。心血管疾病的负担每年都在增加,影响着生活质量。因此,我们旨在检查比拉特医学院教学医院心血管疾病(CVD)患者的生活质量。材料和方法:2023年1月27日至2023年3月27日,在比拉特医学院教学医院对心血管疾病患者进行了一项基于医院的横断面研究。伦理审查委员会批准了这项研究。收集的数据输入到Microsoft Excel 2019中,并通过IBM SPSS statistics 2025进行分析。结果:256例患者中,67例(26.2%)年龄在61-700岁之间,男性156例(60.9%),91例(35.5%)患有冠状动脉疾病。生活质量受影响最小到最大的领域是身体疼痛(81.04±26.02)、心理健康(76.4±15.18)、社会功能(68.1±24.2)、情绪问题引起的角色限制(67.9±43.56)、身体功能(59.02±28.9)、活力(53.67±15.45)、健康总体感知(50.19±15.7)和身体健康引起的角色局限(46.39±44)。结论:心血管疾病患者的生活质量受到影响的因素包括他们的身体健康、对健康的总体感知、能量和活力、身体功能、情绪问题导致的角色限制、社会功能、心理健康和身体疼痛
{"title":"Quality of Life among Patients with Cardiovascular Diseases at Birat Medical College Teaching Hospital","authors":"Madhab Bista, S. Parajuli, R. K. Mehta, P. Shah, Raju Jayshwal, Sinet Pokharel, Himal Pandey","doi":"10.3126/jonmc.v12i1.56345","DOIUrl":"https://doi.org/10.3126/jonmc.v12i1.56345","url":null,"abstract":"Background: Modern healthcare delivery needs to take care of the quality of life of patients. The burden of cardiovascular disease is increasing each year affecting the quality of life. So, we aimed to examine the quality of life of patients with cardiovascular diseases (CVD) at Birat Medical College Teaching Hospital. \u0000Materials and Methods: A hospital based cross sectional study was conducted among cardiovascular disease patients at Birat Medical College Teaching Hospital from 2023 Jan 27 to 2023 March 27.  Ethical clearance was taken from the institutional review committee. The collected data was entered in Microsoft Excel 2019 and analyzed by IBM SPSS statistics 2025. \u0000Results: Among 256 patients, the majority 67(26.2%) were in the age of 61-70 years and male 156(60.9%). Majority 91(35.5%) had coronary artery diseases. The quality of life domains ranging from least  to most  affected were  bodily pain (81.04±26.02), mental health (76.4±15.18), social functioning (68.1±24.2), role limitation due to emotional problems (67.9±43.56), physical functioning (59.02± 28.9), vitality (53.67±15.45), general perception of health (50.19±15.7) and role limitation due to physical health (46.39± 44).    \u0000Conclusion: Patients with cardiovascular disease had their quality of life affected based on their physical health, general perception of health, energy and vitality, physical functioning, role limitation due to emotional problems, social functioning, mental health and bodily pain","PeriodicalId":52824,"journal":{"name":"Journal of Nobel Medical College","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-07-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43952133","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Outcome of Lung Functions in Covid-19 Patients at a Tertiary Care Center of Eastern Nepal 尼泊尔东部三级保健中心Covid-19患者肺功能结局
Pub Date : 2023-07-17 DOI: 10.3126/jonmc.v12i1.56266
P. Koirala, R. K. Mehta, Swastik Raj Koirala, Gajendra Prasad Yadav, S. Parajuli, Santosh Chaudhary
Background: Novel coronavirus infection has myriad clinical manifestations, such as headache, respiratory failure, and long coronavirus disease syndrome. A common cause for admission is pneumonia, and such patients have shown longer periods of respiratory symptoms and exercise intolerance after discharge. The study aimed to determine short-term and long-term lung function outcomes in coronavirus disease patients. Materials and Methods: The prospective, cross-sectional study was conducted in coronavirus disease facility of Birat Medical College Teaching Hospital. A structured proforma including symptoms, modified medical research council dyspnea scale, 6-minute walk test and portable spirometry were recorded during 3 months follow up. Results: A total of 58 coronavirus disease patients were admitted, 4 expired. Common symptoms were dyspnea (98.28%), fever (94.8%), dry cough (86.2%), myalgia (17.2%). Mean Forced expiratory volume in 1 second to forced vital capacity ratio was normal. The mean forced vital capacity was 46.52% at admission, 53.33% at 3 months. The mean forced expiratory flow at 25% to 75% of forced vital capacity was 56.91% at admission, 59.31% at 3 months. Mean values of forced expiratory volume predicted was 47.40% at admission, 51.69% at 3 months. Mean 6-minute walk test distance did not improve during follow-up (240.09m at 1 month, 239.35m at 3 months) and there was no improvement in oxygen saturation at 3 months compared to the first month. Conclusion: Short-term lung function outcome demonstrated persistent dyspnea and development of mixed airways disease in all the survivors. Long-term lung function outcome observed was persistence of dyspnea, mixed airways disease, and low exercise capacity.
背景:新型冠状病毒感染具有多种临床表现,如头痛、呼吸衰竭、长冠状病毒病综合征等。入院的常见原因是肺炎,这类患者出院后表现出较长时间的呼吸道症状和运动不耐受。该研究旨在确定冠状病毒病患者的短期和长期肺功能结局。材料与方法:前瞻性横断面研究在Birat医学院附属附属医院冠状病毒病研究室进行。在3个月的随访中,记录了包括症状、改良的医学研究委员会呼吸困难量表、6分钟步行试验和便携式肺活量测定在内的结构化形式。结果:共收治冠状病毒病患者58例,死亡4例。常见症状为呼吸困难(98.28%)、发热(94.8%)、干咳(86.2%)、肌痛(17.2%)。平均1秒用力呼气量与用力肺活量之比正常。入院时平均用力肺活量为46.52%,3个月时为53.33%。平均用力呼气流量在用力肺活量的25% ~ 75%时,入院时为56.91%,3个月时为59.31%。入院时用力呼气量预测平均值为47.40%,3个月时为51.69%。在随访期间,平均6分钟步行测试距离没有改善(1个月时为240.09米,3个月时为239.35米),3个月时的血氧饱和度与第一个月相比没有改善。结论:所有幸存者的短期肺功能结果显示持续性呼吸困难和混合性气道疾病的发展。观察到的长期肺功能结果是持续呼吸困难、混合性气道疾病和低运动能力。
{"title":"Outcome of Lung Functions in Covid-19 Patients at a Tertiary Care Center of Eastern Nepal","authors":"P. Koirala, R. K. Mehta, Swastik Raj Koirala, Gajendra Prasad Yadav, S. Parajuli, Santosh Chaudhary","doi":"10.3126/jonmc.v12i1.56266","DOIUrl":"https://doi.org/10.3126/jonmc.v12i1.56266","url":null,"abstract":"Background: Novel coronavirus infection has myriad clinical manifestations, such as headache, respiratory failure, and long coronavirus disease syndrome. A common cause for admission is pneumonia, and such patients have shown longer periods of respiratory symptoms and exercise intolerance after discharge. The study aimed to determine short-term and long-term lung function outcomes in coronavirus disease patients. \u0000Materials and Methods: The prospective, cross-sectional study was conducted in coronavirus disease facility of Birat Medical College Teaching Hospital. A structured proforma including symptoms, modified medical research council dyspnea scale, 6-minute walk test and portable spirometry were recorded during 3 months follow up. \u0000Results: A total of 58 coronavirus disease patients were admitted, 4 expired. Common symptoms were dyspnea (98.28%), fever (94.8%), dry cough (86.2%), myalgia (17.2%). Mean Forced expiratory volume in 1 second to forced vital capacity ratio was normal. The mean forced vital capacity was 46.52% at admission, 53.33% at 3 months. The mean forced expiratory flow at 25% to 75% of forced vital capacity was 56.91% at admission, 59.31% at 3 months. Mean values of forced expiratory volume predicted was 47.40% at admission, 51.69% at 3 months. Mean 6-minute walk test distance did not improve during follow-up (240.09m at 1 month, 239.35m at 3 months) and there was no improvement in oxygen saturation at 3 months compared to the first month. \u0000Conclusion: Short-term lung function outcome demonstrated persistent dyspnea and development of mixed airways disease in all the survivors. Long-term lung function outcome observed was persistence of dyspnea, mixed airways disease, and low exercise capacity.","PeriodicalId":52824,"journal":{"name":"Journal of Nobel Medical College","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-07-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43603634","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Sex Differentiation from Fingerprint Ridge Density 指纹脊密度的性别分化
Pub Date : 2023-07-17 DOI: 10.3126/jonmc.v12i1.56264
Jwala Kandel, Samjhana Ghimire, Rashmita Bhandari
Background: Determination of sex is an important parameter other than age, race and stature during forensic identification and crime scene investigation. Females tend to have finer and denser ridges on their fingertips than males. Present study aims at differentiating gender from fingerprint ridge density.Material and Methods: This is a cross sectional study conducted from March 2022 to March 2023 in Nobel Medical College Teaching Hospital, Nepal. Seven hundred fingerprints samples (350 males and 350 females), from 70 Nepalese medical students were collected and analyzed for gender differences. Comparative analysis was done using Student’s t-test (p<0.05). Likelihood ratio and posterior probability using Baye’s theorem were calculated to interpret the possibility of gender differentiation from various fingerprint ridge densities.Results: Students t-test revealed significant difference (p < 0.001) between the fingerprint ridge density of male and female (t= -16.733). The results showed ridge density <14/25mm2and >15/25mm2 are “more likely than not” from males and females respectively. Posterior probability using Baye’s theorem further revealed ridge density <13/25mm2 (C/C1=5.75,P=0.86) and >16/25mm2 (C1/C=4.29, P1=0.84) have higher probability of originating from males and females respectively. No any male and female had ridge density >16/25mm2 and <13/25mm2 respectively.Conclusion: The study revealsstatistically significantlygreater fingerprint ridge densities in female than in male Nepalese medical students.
背景:在法医鉴定和犯罪现场调查中,性别是除年龄、种族和身材以外的重要参数。与男性相比,女性的指尖上往往有更细、更密的脊。本研究旨在利用指纹脊密度进行性别鉴别。材料和方法:这是一项横断面研究,于2022年3月至2023年3月在尼泊尔诺贝尔医学院教学医院进行。来自70名尼泊尔医科学生的700份指纹样本(350名男性和350名女性)被收集并分析了性别差异。比较分析使用学生t检验(p15/25mm2分别来自男性和女性“更有可能”)。贝叶斯定理的后验概率进一步揭示了脊密度16/25mm2 (C1/C=4.29, P1=0.84)分别具有较高的来自雄性和雌性的概率。雄鼠和雌鼠脊密度分别为16/25mm2和13/25mm2。结论:尼泊尔医学生女性指纹脊密度显著高于男性。
{"title":"Sex Differentiation from Fingerprint Ridge Density","authors":"Jwala Kandel, Samjhana Ghimire, Rashmita Bhandari","doi":"10.3126/jonmc.v12i1.56264","DOIUrl":"https://doi.org/10.3126/jonmc.v12i1.56264","url":null,"abstract":"Background: Determination of sex is an important parameter other than age, race and stature during forensic identification and crime scene investigation. Females tend to have finer and denser ridges on their fingertips than males. Present study aims at differentiating gender from fingerprint ridge density.\u0000Material and Methods: This is a cross sectional study conducted from March 2022 to March 2023 in Nobel Medical College Teaching Hospital, Nepal. Seven hundred fingerprints samples (350 males and 350 females), from 70 Nepalese medical students were collected and analyzed for gender differences. Comparative analysis was done using Student’s t-test (p<0.05). Likelihood ratio and posterior probability using Baye’s theorem were calculated to interpret the possibility of gender differentiation from various fingerprint ridge densities.\u0000Results: Students t-test revealed significant difference (p < 0.001) between the fingerprint ridge density of male and female (t= -16.733). The results showed ridge density <14/25mm2and >15/25mm2 are “more likely than not” from males and females respectively. Posterior probability using Baye’s theorem further revealed ridge density <13/25mm2 (C/C1=5.75,P=0.86) and >16/25mm2 (C1/C=4.29, P1=0.84) have higher probability of originating from males and females respectively. No any male and female had ridge density >16/25mm2 and <13/25mm2 respectively.\u0000Conclusion: The study revealsstatistically significantlygreater fingerprint ridge densities in female than in male Nepalese medical students.","PeriodicalId":52824,"journal":{"name":"Journal of Nobel Medical College","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-07-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42288332","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Prediction of Stone Free Rate after Standard Percutaneous Nephrolithotomy using Stone Nephrolithometry Score in Nobel Medical College Teaching hospital – A Prospective Study 诺贝尔医学院教学医院标准经皮肾穿刺取石术后结石游离率的前瞻性研究
Pub Date : 2023-07-17 DOI: 10.3126/jonmc.v12i1.56247
Ram Sagar Shah, Niraj Thapa, Jit Prakash Shrestha, A. Koirala, Kartikesh Mishra, Raju Jayshwal, Sinet Pokharel, Himal Pandey
Background: Amongst all the modalities of treatment for renal stones, percutaneous nephrolithotomy is preferred treatment for large volume renal stone disease. However, percutaneous nephrolithotomy is associated with the risk of postoperative complications and the problem of stone free status. So, a preoperative classification is necessary to grade the complexity of percutaneous nephrolithotomy and STONE (stone size, tract length, degree of obstruction, number of involved calices, and stone essence) nephrolithometry score is one of such kind. Materials and Methods: This is analytical study conducted at the Department of Urology and Kidney Transplant, Nobel Medical College and Teaching Hospital, Biratnagar, Nepal from January 2020 to July 2020. Total 115 patients were included in the study. These patients were subjected for percutaneous nephrolithotomy. Stone clearance was documented at the end of the surgery; on first postoperative day and at 4 weeks. Results: In our study the stone – free rate was 89.6%. 32 patients experienced complications (27.8%). The STONE (stone size, tract length, degree of obstruction, number of involved calices, and stone essence) score correlated with the postoperative stone – free status (P=0.001). The patients rendered stone free had statistically significant lower scores than the patients with residual stones (6.83 ± 1.83 vs 9.83 ± 2.08, P = 0.001). Conclusion: The STONE (stone size, tract length, degree of obstruction, number of involved calices, and stone essence) nephrolithometry score is a simple and easy tool to apply system for predicting complexity in stone clearance with percutaneous nephrolithotomy.
背景:在所有治疗肾结石的方式中,经皮肾镜取石术是大体积肾结石疾病的首选治疗方法。然而,经皮肾镜取石术与术后并发症的风险和无结石状态的问题有关。因此,术前有必要对经皮肾镜取石术和结石的复杂性进行分级(结石大小、尿路长度、阻塞程度、受累肾盏数、结石实质),肾结石测量评分就是其中一种。材料和方法:这是一项分析性研究,于2020年1月至2020年7月在尼泊尔比拉特纳格尔诺贝尔医学院和教学医院泌尿外科和肾脏移植科进行。研究共纳入115例患者。这些患者接受经皮肾镜取石术。手术结束时记录结石清除情况;术后第一天和第4周。结果:本组结石清除率为89.6%。32例出现并发症(27.8%)。结石(结石大小、尿路长度、梗阻程度、受累肾盏数和结石实质)评分与术后无结石状态相关(P=0.001)。结石清除组得分低于结石残留组(6.83±1.83 vs 9.83±2.08,P = 0.001)。结论:结石(结石大小、尿路长度、梗阻程度、受累肾盏数、结石实质)肾结石测量评分是预测经皮肾镜取石术后结石清除复杂性的一种简单易行的工具。
{"title":"Prediction of Stone Free Rate after Standard Percutaneous Nephrolithotomy using Stone Nephrolithometry Score in Nobel Medical College Teaching hospital – A Prospective Study","authors":"Ram Sagar Shah, Niraj Thapa, Jit Prakash Shrestha, A. Koirala, Kartikesh Mishra, Raju Jayshwal, Sinet Pokharel, Himal Pandey","doi":"10.3126/jonmc.v12i1.56247","DOIUrl":"https://doi.org/10.3126/jonmc.v12i1.56247","url":null,"abstract":"Background: Amongst all the modalities of treatment for renal stones, percutaneous nephrolithotomy is preferred treatment for large volume renal stone disease. However, percutaneous nephrolithotomy is associated with the risk of postoperative complications and the problem of stone free status. So, a preoperative classification is necessary to grade the complexity of percutaneous nephrolithotomy and STONE (stone size, tract length, degree of obstruction, number of involved calices, and stone essence) nephrolithometry score is one of such kind. \u0000Materials and Methods: This is analytical study conducted at the Department of Urology and Kidney Transplant, Nobel Medical College and Teaching Hospital, Biratnagar, Nepal from January 2020 to July 2020. Total 115 patients were included in the study. These patients were subjected for percutaneous nephrolithotomy. Stone clearance was documented at the end of the surgery; on first postoperative day and at 4 weeks. \u0000Results: In our study the stone – free rate was 89.6%. 32 patients experienced complications (27.8%). The STONE (stone size, tract length, degree of obstruction, number of involved calices, and stone essence) score correlated with the postoperative stone – free status (P=0.001). The patients rendered stone free had statistically significant lower scores than the patients with residual stones (6.83 ± 1.83 vs 9.83 ± 2.08, P = 0.001). \u0000Conclusion: The STONE (stone size, tract length, degree of obstruction, number of involved calices, and stone essence) nephrolithometry score is a simple and easy tool to apply system for predicting complexity in stone clearance with percutaneous nephrolithotomy.","PeriodicalId":52824,"journal":{"name":"Journal of Nobel Medical College","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-07-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44181124","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
期刊
Journal of Nobel Medical College
全部 Acc. Chem. Res. ACS Applied Bio Materials ACS Appl. Electron. Mater. ACS Appl. Energy Mater. ACS Appl. Mater. Interfaces ACS Appl. Nano Mater. ACS Appl. Polym. Mater. ACS BIOMATER-SCI ENG ACS Catal. ACS Cent. Sci. ACS Chem. Biol. ACS Chemical Health & Safety ACS Chem. Neurosci. ACS Comb. Sci. ACS Earth Space Chem. ACS Energy Lett. ACS Infect. Dis. ACS Macro Lett. ACS Mater. Lett. ACS Med. Chem. Lett. ACS Nano ACS Omega ACS Photonics ACS Sens. ACS Sustainable Chem. Eng. ACS Synth. Biol. Anal. Chem. BIOCHEMISTRY-US Bioconjugate Chem. BIOMACROMOLECULES Chem. Res. Toxicol. Chem. Rev. Chem. Mater. CRYST GROWTH DES ENERG FUEL Environ. Sci. Technol. Environ. Sci. Technol. Lett. Eur. J. Inorg. Chem. IND ENG CHEM RES Inorg. Chem. J. Agric. Food. Chem. J. Chem. Eng. Data J. Chem. Educ. J. Chem. Inf. Model. J. Chem. Theory Comput. J. Med. Chem. J. Nat. Prod. J PROTEOME RES J. Am. Chem. Soc. LANGMUIR MACROMOLECULES Mol. Pharmaceutics Nano Lett. Org. Lett. ORG PROCESS RES DEV ORGANOMETALLICS J. Org. Chem. J. Phys. Chem. J. Phys. Chem. A J. Phys. Chem. B J. Phys. Chem. C J. Phys. Chem. Lett. Analyst Anal. Methods Biomater. Sci. Catal. Sci. Technol. Chem. Commun. Chem. Soc. Rev. CHEM EDUC RES PRACT CRYSTENGCOMM Dalton Trans. Energy Environ. Sci. ENVIRON SCI-NANO ENVIRON SCI-PROC IMP ENVIRON SCI-WAT RES Faraday Discuss. Food Funct. Green Chem. Inorg. Chem. Front. Integr. Biol. J. Anal. At. Spectrom. J. Mater. Chem. A J. Mater. Chem. B J. Mater. Chem. C Lab Chip Mater. Chem. Front. Mater. Horiz. MEDCHEMCOMM Metallomics Mol. Biosyst. Mol. Syst. Des. Eng. Nanoscale Nanoscale Horiz. Nat. Prod. Rep. New J. Chem. Org. Biomol. Chem. Org. Chem. Front. PHOTOCH PHOTOBIO SCI PCCP Polym. Chem.
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
0
微信
客服QQ
Book学术公众号 扫码关注我们
反馈
×
意见反馈
请填写您的意见或建议
请填写您的手机或邮箱
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
现在去查看 取消
×
提示
确定
Book学术官方微信
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术
文献互助 智能选刊 最新文献 互助须知 联系我们:info@booksci.cn
Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。
Copyright © 2023 Book学术 All rights reserved.
ghs 京公网安备 11010802042870号 京ICP备2023020795号-1