Shouqian Wang, Lei Liu, Changxu Li, Qingchun Guan, Yingchao Wang
{"title":"Spleen in situ B-cell marginal zone lymphoma and pancreatic ductal papillary mucinous neoplasm: report of one case and review of literature","authors":"Shouqian Wang, Lei Liu, Changxu Li, Qingchun Guan, Yingchao Wang","doi":"10.3760/CMA.J.ISSN.1006-9801.2019.11.014","DOIUrl":null,"url":null,"abstract":"目的 \n探讨脾脏原位B细胞边缘区淋巴瘤合并胰腺导管内乳头状黏液性肿瘤（IPMN）的临床特征及诊断。 \n \n \n方法 \n回顾性分析吉林大学第一医院收治的1例脾脏原位B细胞边缘区淋巴瘤合并IPMN患者的术前实验室相关检查资料、影像学资料、术后病理资料，并复习相关文献。 \n \n \n结果 \n该患者术后病理结果为脾脏原位B细胞边缘区淋巴瘤合并IPMN。肝胆脾胰多排CT平扫+三期增强扫描示胰体部低强化影，考虑占位性病变；术后骨髓穿刺活组织检查结果示有核细胞形态未见明显异常。术后3个月随访，未见明显异常。 \n \n \n结论 \n脾脏原位B细胞边缘区淋巴瘤合并IPMN临床上十分罕见。脾边缘区淋巴瘤和IPMN的诊断均依赖病理组织学和免疫组织化学。","PeriodicalId":9505,"journal":{"name":"肿瘤研究与临床","volume":null,"pages":null},"PeriodicalIF":0.0000,"publicationDate":"2019-11-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"肿瘤研究与临床","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.3760/CMA.J.ISSN.1006-9801.2019.11.014","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q4","JCRName":"Medicine","Score":null,"Total":0}
Objective To investigate the clinical characteristics and diagnosis of splenic in situ B-cell marginal zone lymphoma combined with pancreatic ductal papillary mucinous tumor (IPMN). Method: A retrospective analysis was conducted on the preoperative laboratory examination data, imaging data, and postoperative pathological data of a patient with splenic in situ B-cell marginal zone lymphoma complicated with IPMN admitted to the First Hospital of Jilin University, and the relevant literature was reviewed. The postoperative pathological result of the patient was splenic in situ B-cell marginal zone lymphoma with IPMN. Multi slice CT scan of liver, gallbladder, spleen, and pancreas combined with three phase enhanced scan shows low contrast enhancement in the body of the pancreas, considering space occupying lesions; The results of postoperative bone marrow biopsy showed no significant abnormalities in the morphology of nuclear cells. After 3 months of follow-up, no obvious abnormalities were found. Conclusion: In situ B-cell border zone lymphoma of the spleen with IPMN is very rare in clinical practice. The diagnosis of splenic marginal zone lymphoma and IPMN relies on histopathology and immunohistochemistry.
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