{"title":"Inactivation of sars-cov-2 by povidone-iodine products: Implications for effective mouth rinsing and gargling","authors":"H. Kariwa, H. Sawa, Shintaro Kobayashi","doi":"10.14943/jjvr.69.3.183","DOIUrl":null,"url":null,"abstract":"Coronavirus disease 2019 (COVID-19) is caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). SARS-CoV-2 is transmitted mainly via droplets and contact. The implementation of infection control measures is important to reduce the number of COVID-19 cases. Thus, the ability of several povidone-iodine (PVP-I) products to inactivate SARS-CoV-2 was evaluated based on their in vitro inactivation efficacy. PVP-I solutions such as Isodine Gargle® (ethical and consumer products), Isodine Gargle C®, and Isodine Nodo Fresh® for 30 or 60 s decreased the viral infectivity level from 2-4 × 106 TCID50/ml to below the detectable level (> 99.9% reduction). Our results indicate that the use of Isodine® mouthwash and gargle products is an effective infection control measure against SARS-CoV-2.","PeriodicalId":56285,"journal":{"name":"Japanese Journal of Veterinary Research","volume":null,"pages":null},"PeriodicalIF":0.4000,"publicationDate":"2021-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"4","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Japanese Journal of Veterinary Research","FirstCategoryId":"97","ListUrlMain":"https://doi.org/10.14943/jjvr.69.3.183","RegionNum":4,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q4","JCRName":"VETERINARY SCIENCES","Score":null,"Total":0}
引用次数: 4
Abstract
Coronavirus disease 2019 (COVID-19) is caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). SARS-CoV-2 is transmitted mainly via droplets and contact. The implementation of infection control measures is important to reduce the number of COVID-19 cases. Thus, the ability of several povidone-iodine (PVP-I) products to inactivate SARS-CoV-2 was evaluated based on their in vitro inactivation efficacy. PVP-I solutions such as Isodine Gargle® (ethical and consumer products), Isodine Gargle C®, and Isodine Nodo Fresh® for 30 or 60 s decreased the viral infectivity level from 2-4 × 106 TCID50/ml to below the detectable level (> 99.9% reduction). Our results indicate that the use of Isodine® mouthwash and gargle products is an effective infection control measure against SARS-CoV-2.
期刊介绍：
The Japanese Journal of Veterinary Research (JJVR) quarterly publishes peer-reviewed articles on all aspects of veterinary science. JJVR was originally published as a “University Journal” of veterinary science at Hokkaido University from more than 60 years ago. Currently, JJVR, is Japan’s leading scientific veterinary journal, and provides valuable information for the development of veterinary science by welcoming contributions from researchers worldwide.
JJVR offers online submission for Regular Papers, Short Communications, and Review Articles that are unpublished and not being considered for publication elsewhere. Research areas include:
Anatomy, Physiology, Biochemistry, Pharmacology, Microbiology, Infectious diseases, Parasitology, Laboratory Animal Science and Medicine, Internal Medicine, Surgery, Pathology, Theriogenology, Molecular Medicine, Public Health, Radiation Biology, Toxicology, Wildlife Biology and Medicine, Veterinary Hygiene, The other fields related to veterinary science.
京公网安备 11010802042870号
京ICP备2023020795号-1
分享
求助内容：
应助结果提醒方式：
扫码关注我们
