Advances in the study of antibodies associated with myasthenia gravis

Abstract

As an autoimmune disease involving the neuromuscular junction, the pathogenesis of myasthenia gravis(MG) is closely related to autoimmune antibodies.Regarding related antibodies, acetylcholine receptor antibody(AChR-Ab) is the most studied and clear.In recent years, researchers have began to study antibodies other than AChR-Ab due to the presence of AChR-Ab-negative MG patients, such as muscle-specific tyrosine kinase antibodies, low-density lipoprotein 4 antibodies, and explore the corresponding treatment options.This article reviewed the research progress of MG related antibodies, and provided clinical evidence and reference for the future treatment of this disease. Key words: Antibody; Myasthenia gravis; Autoimmune disease; Thyroid