Bovine colostrum: A source of bioactive compounds for prevention and treatment of gastrointestinal disorders

IF 4.1 Q2 FOOD SCIENCE & TECHNOLOGY NFS Journal Pub Date : 2021-11-01 DOI:10.1016/j.nfs.2021.10.001

Rhaabe D.S. Gomes , Katya Anaya , Alyne B.S. Galdino , Juliana P.F. Oliveira , Marco A.S. Gama , Caroline A.C.X. Medeiros , Elaine C. Gavioli , Ana Lúcia F. Porto , Adriano H.N. Rangel

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引用次数: 13

Abstract

Bovine colostrum is a rich source of nutrients and biologically active molecules known to be able to modulate the human immune system, such as lactoferrin, lysozyme, lactoperoxidase, immunoglobulins and growth factors. This comprehensive review aimed to gather evidence from animal experimentation and clinical trials that investigated the potential effects of bovine colostrum in preventing and treating diseases that affect the human gastrointestinal tract. Considered safe for human consumption, BC or its isolate components were used against a range of different gastrointestinal disorders. Beneficial effects were observed in several conditions: gastrointestinal infections, infectious diarrhoea, drug-induced lesions, gut-barrier malfunction, and inflammatory bowel disease. Under proper processing to maintain its components' integrity, BC products are valuable supplements with high nutraceutical value, capable of promoting and restoring gastrointestinal health.

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牛初乳:预防和治疗胃肠道疾病的生物活性化合物的来源

牛初乳含有丰富的营养物质和生物活性分子，能够调节人体免疫系统，如乳铁蛋白、溶菌酶、乳过氧化物酶、免疫球蛋白和生长因子。本综述旨在从动物实验和临床试验中收集证据，研究牛初乳在预防和治疗影响人类胃肠道疾病方面的潜在作用。考虑到对人类消费是安全的，BC或其分离成分被用于治疗一系列不同的胃肠道疾病。在几种情况下观察到有益的效果:胃肠道感染，感染性腹泻，药物引起的病变，肠屏障功能障碍和炎症性肠病。经过适当的加工，保持其成分的完整性，BC产品具有很高的营养价值，能够促进和恢复胃肠道健康。

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来源期刊

NFS Journal Agricultural and Biological Sciences-Food Science

CiteScore

11.10

自引率

0.00%

发文量

审稿时长

29 days

期刊介绍： The NFS Journal publishes high-quality original research articles and methods papers presenting cutting-edge scientific advances as well as review articles on current topics in all areas of nutrition and food science. The journal particularly invites submission of articles that deal with subjects on the interface of nutrition and food research and thus connect both disciplines. The journal offers a new form of submission Registered Reports (see below). NFS Journal is a forum for research in the following areas: • Understanding the role of dietary factors (macronutrients and micronutrients, phytochemicals, bioactive lipids and peptides etc.) in disease prevention and maintenance of optimum health • Prevention of diet- and age-related pathologies by nutritional approaches • Advances in food technology and food formulation (e.g. novel strategies to reduce salt, sugar, or trans-fat contents etc.) • Nutrition and food genomics, transcriptomics, proteomics, and metabolomics • Identification and characterization of food components • Dietary sources and intake of nutrients and bioactive compounds • Food authentication and quality • Nanotechnology in nutritional and food sciences • (Bio-) Functional properties of foods • Development and validation of novel analytical and research methods • Age- and gender-differences in biological activities and the bioavailability of vitamins, minerals, and phytochemicals and other dietary factors • Food safety and toxicology • Food and nutrition security • Sustainability of food production