Comparison between MyoRing and 355°KERATACx in the management of keratoconus

E. Edrees, Fekry Zaher, A. Assaf, M. Yousef, A. Ebeid
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Abstract

Background Intracorneal implants have been proposed over the years as a possible easier way for managing keratoconus, having a favorable influence on the course of the disease. KERATACx is a relatively new form of intracorneal ring segments that has been recently introduced but not thoroughly studied regarding its safety and efficacy. Moreover, implanting a complete intrastromal ring into a corneal pocket, MyoRing (Dioptex GmbH, Austria), is an alternative technique, which can be considered safe, effective, and relatively easy for the treatment of keratoconus. Aim To compare between the effect of MyoRing and KERATACx corneal implants as new modalities of treatment on the visual acuity, as well as assess corneal topography findings in cases with moderate to severe keratoconus. Patients and methods Our study is a prospective comparative study conducted at specialized eye centers in Cairo. A total of 20 keratoconic eyes were eventually recruited. Overall, 10 of those eyes had 355° intracorneal ring segment implants (KERATACx ring segments) inserted into a femtosecond laser-created corneal tunnel at a depth of 75% of the thinnest location at the proposed tunnel site (group A), whereas the other 10 eyes had complete ring (MyoRing) implantation into a femtosecond laser-created corneal pocket at a 300-μm corneal depth (group B), by the same designated surgeon. The study was approved by the Ethics Committee of Ain-Shams University. Results Both types were proven to be statistically effective, with no statistically significant differences between the two groups related to any of the followed up parameters. In fact, both proved safe, effective, and reliable methods for managing keratoconus, with no difference of importance even to the degree of myopic refractive error correction. There were no significant intraoperative or postoperative complications reported within both groups throughout the whole study and follow-up period, but in turn, stability of the achieved results was found in both groups. Conclusion Both MyoRing and KERATACx were found to be equally effective, safe, and reliable methods for keratoconus management.
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MyoRing与355°角锥治疗圆锥角膜的比较
背景多年来,角膜内植入物被认为是治疗圆锥角膜的一种可能更简单的方法,对圆锥角膜的病程有着有利的影响。KERATACx是一种相对较新的角膜环节段形式,最近被引入,但其安全性和有效性尚未得到彻底研究。此外,将一个完整的层内环植入角膜袋MyoRing(Dioptex GmbH,奥地利)是一种替代技术,可以被认为是安全、有效且相对容易治疗圆锥角膜的。目的比较MyoRing和KERATACx角膜植入物作为新的治疗方式对视力的影响,并评估中重度圆锥角膜的角膜地形图表现。患者和方法我们的研究是在开罗的专门眼科中心进行的前瞻性比较研究。最终共招募了20只圆锥角膜眼。总体而言,其中10只眼睛将355°角膜环段植入物(KEATACx环段)插入飞秒激光创建的角膜隧道中,深度为拟议隧道部位最薄位置的75%(a组),而其他10只眼睛则将完整的环段(MyoRing)植入飞秒激光创建、角膜深度为300μm的角膜袋中(B组),由同一位指定的外科医生。这项研究得到了艾因沙姆斯大学伦理委员会的批准。结果两种类型均被证明具有统计学有效性,两组在任何随访参数方面均无统计学显著差异。事实上,这两种治疗圆锥角膜的方法都被证明是安全、有效和可靠的,即使在近视屈光不正矫正的程度上也没有重要差异。在整个研究和随访期间,两组均未报告显著的术中或术后并发症,但反过来,两组的疗效稳定。结论MyoRing和KERATACx是治疗圆锥角膜同样有效、安全、可靠的方法。
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审稿时长
19 weeks
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