Use of Doubling Number as an Arithmetic Measure of Plant Cell Growth and Metal-Induced Cell Growth Inhibition

IF 1 Q3 MULTIDISCIPLINARY SCIENCES gazi university journal of science Pub Date : 2023-04-20 DOI:10.35378/gujs.1244209
M. Metin, T. Kawano
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Abstract

Cell growth inhibition is generally handled as a measure of toxicity. Shortly, more toxicity implies more growth inhibition. Then, the question arises; How to calculate & evaluate cell growth inhibition in a universal manner? Actually, the method for calculating growth inhibition is not considered to be a central issue, in general. There are various approaches for calculating cell growth. Among these approaches, two of them are highly easy and popular, subtraction-based and division-based calculations. However, these two methods for the calculation of cell growth do not strongly reflect the nature of cell growth. Alternatively, the use of a doubling number-based formulation can provide a better approach and performance in the evaluation of cell growth and cell growth inhibition unless the culture attains the confluent status. Here, we discussed different methods of growth calculation which we applied to the study of “growth inhibition of BY-2 cells under Cd exposure”.
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使用倍增数作为植物细胞生长和金属诱导的细胞生长抑制的算术测量
细胞生长抑制通常被视为毒性的衡量标准。不久,毒性越大,生长抑制作用就越大。然后,问题出现了;如何以通用的方式计算和评估细胞生长抑制?实际上,一般来说,计算生长抑制的方法并不是一个中心问题。有多种计算细胞生长的方法。在这些方法中,有两种非常简单和流行,即基于减法和基于除法的计算。然而,这两种计算细胞生长的方法并不能很好地反映细胞生长的性质。或者,使用基于加倍数的制剂可以在评估细胞生长和细胞生长抑制方面提供更好的方法和性能,除非培养物达到融合状态。在这里,我们讨论了我们应用于“镉暴露下BY-2细胞生长抑制”研究的不同生长计算方法。
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来源期刊
gazi university journal of science
gazi university journal of science MULTIDISCIPLINARY SCIENCES-
CiteScore
1.60
自引率
11.10%
发文量
87
期刊介绍: The scope of the “Gazi University Journal of Science” comprises such as original research on all aspects of basic science, engineering and technology. Original research results, scientific reviews and short communication notes in various fields of science and technology are considered for publication. The publication language of the journal is English. Manuscripts previously published in another journal are not accepted. Manuscripts with a suitable balance of practice and theory are preferred. A review article is expected to give in-depth information and satisfying evaluation of a specific scientific or technologic subject, supported with an extensive list of sources. Short communication notes prepared by researchers who would like to share the first outcomes of their on-going, original research work are welcome.
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