Portosystemic Shunt in A Puppy Poodle and Medical Treatment: Case report

E. Koral, M. Durgut
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Abstract

The case includes a 7-month-old puppy poodle applied to a private hospital for weakness, tremors and seizure attacks. Clinical examination findings were normal. From blood samples, biochemical parameter measurements were carried out. The values of alkaline phosphatase (ALP), alanine aminotransferase (ALT), ammonia and fasting serum bile acids were high and the blood urea nitrogen (BUN) value was low. Ultrasonographic examination, shunted vein in the liver to the vena cava caudalis, that is, colour Doppler observed the extrahepatic shunt and turbulent flow in this shunted. Depending on clinical, laboratory (hemogram and biochemistry) and ultrasonographic observations, portosystemic shunt (PSS) was diagnosed and controlled one month after the treatment was recommended. The medical treatment included a hepatic formula diet (liver care), lactulose 0.5 ml/kg three times a day, metronidazole 15 mg/kg twice a day, S-adenosyl Methionine 15 mg/kg once a day, 400 international unite (IU) vitamin E once a day for 30 days. When turbulent flow is observed in the shunted vein in the liver to vena cava caudalis, ultrasound examination with color Doppler can help diagnose portosystemic shunt. After the treatment, clinical improvement was observed and clinical symptoms of hepatic encephalopathy including seizures and tremors, disappeared completely. Determination of turbulent flow with colour Doppler and decreased portal flow velocity with portal hypertension with PW-Doppler ultrasonography are important for the diagnosis of the portosystemic shunt. It was concluded that medical treatments might help before surgical treatments in portosystemic shunts. ـــــــــــــــــــــــــــــــــــــــــ
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幼犬门静脉系统分流及治疗:个案报告
该案件包括一只7个月大的贵宾犬,因虚弱、震颤和癫痫发作而向一家私立医院申请。临床检查结果正常。从血液样本中进行生化参数测量。血清碱性磷酸酶(ALP)、丙氨酸转氨酶(ALT)、氨和空腹胆汁酸偏高,血尿素氮(BUN)偏低。超声检查,肝内分流静脉至尾腔静脉,即彩色多普勒观察到肝外分流及此分流内的湍流。根据临床、实验室(血象、生化)和超声观察,在推荐治疗一个月后诊断并控制门静脉系统分流(PSS)。治疗包括肝脏配方饮食(肝脏护理)、乳果糖0.5 ml/kg每日3次、甲硝唑15 mg/kg每日2次、s -腺苷蛋氨酸15 mg/kg每日1次、400国际单位维生素E每日1次,连用30天。当肝至尾腔静脉分流静脉出现湍流时,彩色多普勒超声检查有助于诊断门静脉系统分流。治疗后,肝性脑病临床症状好转,癫痫发作、震颤等症状完全消失。彩色多普勒超声检测门静脉湍流和pw -多普勒超声检测门静脉高压症门静脉流速降低对门静脉分流的诊断有重要意义。结论在门静脉系统分流的手术治疗之前,药物治疗是有帮助的。ـــــــــــــــــــــــــــــــــــــــــ
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来源期刊
CiteScore
1.10
自引率
0.00%
发文量
44
审稿时长
5 weeks
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