Prevalence and Antibiogram of Bacterial Uropathogens from a Tertiary Care Hospital of Eastern Nepal

K. Shrestha, P. Singh, K. R. Yadav, G. Singh
{"title":"Prevalence and Antibiogram of Bacterial Uropathogens from a Tertiary Care Hospital of Eastern Nepal","authors":"K. Shrestha, P. Singh, K. R. Yadav, G. Singh","doi":"10.3126/jonmc.v12i1.56340","DOIUrl":null,"url":null,"abstract":"Background: Urinary tract infection (UTI) is defined as growth of micro-organisms >105 CFU/ml in mid-stream urine samples. [1] Globally, urinary tract infection is considered a major public health concern with the second most common bacterial infection affecting individuals of different ages. It is estimated that worldwide 150 million cases of UTI occur per year and bacteria are responsible for about 95% of all the cases with each year. [3, 4] This study was designed to describe the pattern of microorganisms causing UTI and their antibiotic sensitivity. \nMaterials and Methods: This is a hospital based cross-sectional study conducted in the Department of Microbiology from January 2022 to June 2022 after taking ethical approval from Institutional Review Committee, Nobel Medical College and Teaching Hospital, Biratnagar, Nepal. The patient profiles or records visiting a tertiary care hospital of both sex and every age group who were having symptoms and clinical diagnosis of urinary tract infection were included. \nResults: A total of 2247 urine samples were collected, 501(22.29%) of the urine sample yielded significant growth of uropathogenes. The most common bacteria was found to be Escherichia coli (E. coli) that accounts for 73.05% followed by Enterococcus species 11.57%, Klebsiella pneumoniae 8.98% and amikacin and nitrofurantoin was found to be the most sensitive antibiotic to gram negative uropathogens. \nConclusion: The prevalence of uropathogenes was found to be higher in our study. Significant bacteriuria was seen in the female than male. The total number of patient with culture positivity was higher in younger age groups with high frequency of antibiotic resistance","PeriodicalId":52824,"journal":{"name":"Journal of Nobel Medical College","volume":null,"pages":null},"PeriodicalIF":0.0000,"publicationDate":"2023-07-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Journal of Nobel Medical College","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.3126/jonmc.v12i1.56340","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 0

Abstract

Background: Urinary tract infection (UTI) is defined as growth of micro-organisms >105 CFU/ml in mid-stream urine samples. [1] Globally, urinary tract infection is considered a major public health concern with the second most common bacterial infection affecting individuals of different ages. It is estimated that worldwide 150 million cases of UTI occur per year and bacteria are responsible for about 95% of all the cases with each year. [3, 4] This study was designed to describe the pattern of microorganisms causing UTI and their antibiotic sensitivity. Materials and Methods: This is a hospital based cross-sectional study conducted in the Department of Microbiology from January 2022 to June 2022 after taking ethical approval from Institutional Review Committee, Nobel Medical College and Teaching Hospital, Biratnagar, Nepal. The patient profiles or records visiting a tertiary care hospital of both sex and every age group who were having symptoms and clinical diagnosis of urinary tract infection were included. Results: A total of 2247 urine samples were collected, 501(22.29%) of the urine sample yielded significant growth of uropathogenes. The most common bacteria was found to be Escherichia coli (E. coli) that accounts for 73.05% followed by Enterococcus species 11.57%, Klebsiella pneumoniae 8.98% and amikacin and nitrofurantoin was found to be the most sensitive antibiotic to gram negative uropathogens. Conclusion: The prevalence of uropathogenes was found to be higher in our study. Significant bacteriuria was seen in the female than male. The total number of patient with culture positivity was higher in younger age groups with high frequency of antibiotic resistance
查看原文
分享 分享
微信好友 朋友圈 QQ好友 复制链接
本刊更多论文
尼泊尔东部某三级医院尿路细菌病原菌的流行及抗生素谱分析
背景:尿路感染(UTI)是指中期尿液样本中大于105CFU/ml的微生物生长。[1] 在全球范围内,尿路感染被认为是一个主要的公共卫生问题,是影响不同年龄段人群的第二常见细菌感染。据估计,全球每年发生1.5亿例尿路感染病例,细菌约占每年所有病例的95%。[3,4]本研究旨在描述引起尿路感染的微生物模式及其抗生素敏感性。材料和方法:这是一项基于医院的横断面研究,于2022年1月至2022年6月在获得尼泊尔比拉特纳格尔诺贝尔医学院和教学医院机构审查委员会的伦理批准后,在微生物系进行。包括有尿路感染症状和临床诊断的性别和每个年龄组的三级护理医院就诊的患者档案或记录。结果:共采集了2247份尿液样本,其中501份(22.29%)的尿液样本产生了显著的泌尿系生长。最常见的细菌是大肠杆菌(E.coli),占73.05%,其次是肠球菌11.57%,肺炎克雷伯菌8.98%,阿米卡星和呋喃妥因是对革兰氏阴性尿路病原体最敏感的抗生素。结论:在我们的研究中发现泌尿系致病基因的患病率较高。女性明显多于男性。在抗生素耐药性高的年轻群体中,培养阳性患者的总数更高
本文章由计算机程序翻译,如有差异,请以英文原文为准。
求助全文
约1分钟内获得全文 去求助
来源期刊
自引率
0.00%
发文量
19
审稿时长
16 weeks
期刊最新文献
Professional Values among Undergraduate Nursing Students in Nobel Medical College Teaching Hospital Sex Differentiation from Fingerprint Ridge Density A Comparative Study of the Safety and Efficacy of Amlodipine and Enalapril when Prescribed as Monotherapy in Patients with Isolated Systolic Hypertension Outcome of Lung Functions in Covid-19 Patients at a Tertiary Care Center of Eastern Nepal Quality of Life among Patients with Cardiovascular Diseases at Birat Medical College Teaching Hospital
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
现在去查看 取消
×
提示
确定
0
微信
客服QQ
Book学术公众号 扫码关注我们
反馈
×
意见反馈
请填写您的意见或建议
请填写您的手机或邮箱
已复制链接
已复制链接
快去分享给好友吧!
我知道了
×
扫码分享
扫码分享
Book学术官方微信
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术
文献互助 智能选刊 最新文献 互助须知 联系我们:info@booksci.cn
Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。
Copyright © 2023 Book学术 All rights reserved.
ghs 京公网安备 11010802042870号 京ICP备2023020795号-1