Editorial: Biosynthesis of bio-inspired nanoparticles/nanomaterials and evaluation of their therapeutic potential in the medical field

IF 4.1 Q2 MATERIALS SCIENCE, MULTIDISCIPLINARY Frontiers in Nanotechnology Pub Date : 2023-04-17 DOI:10.3389/fnano.2023.1198994
F. A. Almeida, R. Srinivasan, S. Vijayakumar
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Abstract

Recent advancement in nanoscience and nanotechnology has given us scope for developing biomimetic and biocompatible nanoparticles/nanomaterials using natural products. Nanoparticles/nanomaterials exhibit remarkable physicochemical and biological properties, which are entirely distinct from their bulk materials, making them ideal candidates for biological applications. The plant, microorganisms, and biopolymersbased nanoparticles/nanomaterials are highly advantageous compared to those involving chemical reductants. The biological synthesis method uses eco-friendly solvents and nontoxic chemicals and thereby helps in minimizing the release of hazardous wastes to the environment. In recent years, widespread microbial infections and mosquito-borne parasitic diseases have been a major threat to humans. In addition, dreadful diseases like cancer have become more common and bring massive mortality to human populations. Many of the currently available growth inhibitory agents and chemotherapeutics are too expensive, cause drug resistance, and have numerous side effects. In this scenario, developing novel therapeutic agents that are cost-effective, safe, and without any side effects is of utmost importance. The development of biological nanoparticles/nanomaterials either from plants, microorganisms, or biopolymers is the need of the hour. Most of the newly developed bionanoparticles/bionanomaterials are promising and have significantly contributed to preventing ailments. This Research Topic, “Biosynthesis of bio-inspired nanoparticles/nanomaterials and evaluation of their therapeutic potential in the medical field”, aimed to include the synthesis, physicochemical characterization, in vitro and in vivo evaluation of the antimicrobial, anti-biofilm, anti-quorum sensing, antiviral, anti-infective, and anti-cancer properties of bionanoparticles/bionanomaterials, as well as their application in the treatment and diagnosis of diseases. OPEN ACCESS
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社论:仿生纳米颗粒/纳米材料的生物合成及其在医学领域的治疗潜力评估
纳米科学和纳米技术的最新进展为我们利用天然产物开发仿生和生物相容的纳米颗粒/纳米材料提供了空间。纳米颗粒/纳米材料表现出显著的物理化学和生物特性,这与它们的本体材料完全不同,使它们成为生物应用的理想候选者。与那些涉及化学还原剂的纳米颗粒相比,植物、微生物和生物聚合物基纳米颗粒/纳米材料是非常有利的。生物合成方法使用环保溶剂和无毒化学品,从而有助于最大限度地减少危险废物向环境的释放。近年来,广泛的微生物感染和蚊子传播的寄生虫病一直是对人类的主要威胁。此外,像癌症这样可怕的疾病变得越来越普遍,给人类带来了巨大的死亡。目前可用的许多生长抑制剂和化疗药物过于昂贵,会引起耐药性,并有许多副作用。在这种情况下,开发具有成本效益、安全且没有任何副作用的新型治疗剂至关重要。从植物、微生物或生物聚合物中开发生物纳米颗粒/纳米材料是时代的需要。大多数新开发的仿生物品/仿生材料都很有前景,并对预防疾病做出了重大贡献。本研究主题为“生物纳米颗粒/纳米材料的生物合成及其在医学领域的治疗潜力评估”,旨在包括生物制品/生物材料的抗菌、抗生物膜、抗群体感应、抗病毒、抗感染和抗癌特性的合成、理化表征、体外和体内评估,以及它们在疾病治疗和诊断中的应用。开放存取
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来源期刊
Frontiers in Nanotechnology
Frontiers in Nanotechnology Engineering-Electrical and Electronic Engineering
CiteScore
7.10
自引率
0.00%
发文量
96
审稿时长
13 weeks
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