The denouement of ozone therapy vying to chlorhexidine in non surgical periodontal therapy

Q3 Biochemistry, Genetics and Molecular Biology Journal of Cellular Biotechnology Pub Date : 2022-08-27 DOI:10.3233/jcb-220073
G. Pendyala, S. Joshi, A. Mani, Sudhir Dhole, P. Kale
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引用次数: 2

Abstract

BACKGROUND: Scaling and root planing [SRP] being the mainstay of treatment of periodontitis encompasses unambiguous impediments. antiseptics represent an aid to nonsurgical periodontal therapy. OBJECTIVE: This randomized controlled, split mouth study design with an observation period of three months aims to clinically evaluate the efficacy of ozonised oil and chlorhexidine as an adjunct to SRP. METHODS: Twenty-five patients of both sexes with an age range of 30–65 years diagnosed with chronic periodontitis and having a periodontal probe depth (PD)≥5 mm and CAL≥3 mm on at least 1 site in each quadrant were included in this randomised split mouth design study. Patients were allocated in 2 experimental treatment groups as SRP + chlorhexidine gel (control sites) and with SRP + ozone oil (test sites). The plaque index (PI), gingival index (GI), and periodontal pocket depth (PPD), clinical attachment level (CAL) were recorded at baseline data and after 30 days post-baseline. RESULTS: The present study showed significant results in both the groups with regards to the improvement in the clinical parameters. When comparison was made between the two groups, it has been assessed that the use of the ozonized oil in addition to SRP did not show significant differences when compared to conventional SRP + chlorhexidine. CONCLUSION: For bye to SRP, ozonized oil can be considered as a viable alternative to chlorhexidine in the treatment of periodontitis, especially considering its low toxicity compared to chlorhexidine.
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臭氧治疗与氯己定在非手术牙周治疗中的竞争结局
背景:牙周炎的主要治疗方法是刮治和牙根刮治,其中包含明确的障碍。杀菌剂是非手术牙周治疗的辅助手段。目的:这项随机对照、裂口研究设计,观察期为3个月,旨在临床评价臭氧化油和氯己定作为SRP辅助治疗的疗效。方法:年龄在30-65岁之间的25例诊断为慢性牙周炎且牙周探针深度(PD)≥5 mm且CAL≥3 mm的患者在每个象限至少有1个部位被纳入这项随机裂口设计研究。将患者分为SRP +氯己定凝胶(对照点)和SRP +臭氧油(试验点)2个实验治疗组。在基线数据和基线后30天记录菌斑指数(PI)、牙龈指数(GI)、牙周袋深度(PPD)、临床附着水平(CAL)。结果:两组患者的临床指标均有显著改善。当两组进行比较时,经评估,与常规SRP +氯己定相比,除SRP外使用臭氧化油没有显着差异。结论:臭氧化油与氯己定相比毒性较低,可作为替代SRP治疗牙周炎的可行选择。
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来源期刊
Journal of Cellular Biotechnology
Journal of Cellular Biotechnology Biochemistry, Genetics and Molecular Biology-Biotechnology
CiteScore
0.70
自引率
0.00%
发文量
13
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