Presence of Psychoactive Substances in Toxicological Examination of Children and Adolescents Victims of Violent Deaths in Sao Paulo: 2014-2016

Ivan Dieb Miziara
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Abstract

The growing use of both licit and illicit drugs by children and adolescents raises concerns on the part of society as a whole. This is because the health system is overloaded with several avoidable hospitalizations, resulting in several years of life lost in this age group, or for demanding new public health policies to combat the sale and trafficking of these drugs. The present study evaluated 47 cases of deaths due to external causes that were referred to the IML of the state of São Paulo between the years of 2014 and 2016 and analyzed the concomitance of these cases with the positivity of the toxicological test, in order to establish a relationship between the deaths and drugs most frequently encountered. The selected group consisted of 08 (17.02%) women and 39 (82.98%) men. The substances identified in the female group were ethyl alcohol (two cases-25%); trichloroethylene (two cases-25%); carbon monoxide (one case-12.5%); trichloroethylene and chloroform (one case-12.5%); cocaine and carbamate (one case-12.5%); and tricyclic antidepressant (one case-12.5%). Thirty-nine toxicological tests of male victims were evaluated, of which alcohol alone was present in 20 tests, representing a rate of 51.28%, in a blood concentration ranging from 0.5 to 4.4g/L. It was concluded that alcohol is the most commonly found substance, but trichloroethylene also has an important role.
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2014-2016年圣保罗暴力死亡儿童和青少年受害者毒理学检查中精神活性物质的存在
儿童和青少年越来越多地使用合法和非法药物引起了整个社会的关注。这是因为卫生系统因几次本可避免的住院治疗而超负荷,导致这一年龄组的生命损失数年,或者要求制定新的公共卫生政策以打击这些药物的销售和贩运。本研究评估了2014年至2016年期间提交给圣保罗州IML的47例外因死亡病例,并分析了这些病例与毒理学试验阳性的相关性,以建立死亡与最常遇到的药物之间的关系。其中女性08例(17.02%),男性39例(82.98%)。在女性组中发现的物质是乙醇(2例-25%);三氯乙烯(2例-25%);一氧化碳(1例,12.5%);三氯乙烯和氯仿(1例,12.5%);可卡因和氨基甲酸酯(1例,12.5%);三环类抗抑郁药(1例,12.5%)。对男性受害者进行了39次毒理学测试,其中20次测试中仅检测到酒精,占51.28%,血液浓度为0.5至4.4g/L。结论是,酒精是最常见的物质,但三氯乙烯也有重要作用。
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