Preparation, Characterization and Antimicrobial Activity of Pd(II), Zn(II) and Cu(II) Complexes of Benzimidazoles and Schiff Bases Including Ferrocene Group

IF 0.4 Q4 CHEMISTRY, MULTIDISCIPLINARY Jordan Journal of Chemistry Pub Date : 2022-12-01 DOI:10.47014/17.3.3
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引用次数: 0

Abstract

PdCl2, ZnCl2 and CuCl2 complexes of three benzimidazole derivatives and two Schiff bases having the ferrocene group were synthesized and characterized. It was unexpectedly noticed that the Pd(II) and Zn(II) complexes exhibit paramagnetic characters corresponding to about one electron caused by the ferrocene moiety. For the same reason, the magnetic moment value of the Cu(II) complexes was also higher than the anticipated values. Besides, the antimicrobial activity of the complexes was investigated against six bacteria and three fungi. Comparing the ligands, the Schiff bases exhibited higher antimicrobial activity than the benzimidazole derivatives, especially on Gram+ bacteria. Among all compounds investigated in this work, [Zn(SB1)2]·2H2O showed the highest activity against S. epidermidis and S. aureus which are Gram+ bacteria.
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含二茂铁基团的苯并咪唑、锌、铜配合物的制备、表征及抗菌活性研究
合成并表征了三种苯并咪唑衍生物和两种具有二茂铁基团的席夫碱的PdCl2、ZnCl2和CuCl2配合物。出乎意料地注意到,Pd(II)和Zn(II)配合物表现出对应于由二茂铁部分引起的大约一个电子的顺磁性特征。出于同样的原因,Cu(II)配合物的磁矩值也高于预期值。此外,研究了复合物对6种细菌和3种真菌的抗菌活性。与配体相比,Schiff碱比苯并咪唑衍生物表现出更高的抗菌活性,尤其是对革兰氏+菌。在本研究的所有化合物中,[Zn(SB1)2]·2H2O对革兰氏+菌表皮葡萄球菌和金黄色葡萄球菌表现出最高的活性。
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来源期刊
Jordan Journal of Chemistry
Jordan Journal of Chemistry CHEMISTRY, MULTIDISCIPLINARY-
CiteScore
0.50
自引率
0.00%
发文量
7
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