Application of ECMO in the treatment of severe adenovirus pneumonia

Zi-hao Yang
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Abstract

Adenovirus is one of the common pathogens causing respiratory tract infection in children, which can cause severe pneumonia.Severe adenovirus pneumonia has an acute onset, rapid progress, and many complications, but there is no specific treatment and the mortality rate is high.Mechanical ventilation is an important means of respiratory support for the treatment of severe adenoviral pneumonia, and ventilator-associated lung injury is an inevitable drawback of mechanical ventilation.ECMO can replace and support cardiopulmonary function for a long time, reduce the occurrence of such damage, and improve oxygenation.When patients with severe adenovirus pneumonia develop respiratory failure or ARDS, and conventional treatment fails to improve hypoxemia, or accompanied by air leakage and other complications, ECMO treatment should be considered.However, there are few relevant studies in China, and further experience needs to be accumulated in the selection of respiratory support modes, intervention opportunities and management points of ECMO respiratory support for severe adenovirus pneumonia. Key words: Extracorporeal membrane oxygenation; Severe adenovirus pneumonia; Respiratory support
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ECMO在重症腺病毒肺炎治疗中的应用
腺病毒是引起儿童呼吸道感染的常见病原体之一,可导致严重肺炎。重型腺病毒肺炎发病急,进展快,并发症多,但尚无特效治疗,死亡率高。机械通气是治疗严重腺病毒性肺炎的重要呼吸支持手段,而呼吸机相关性肺损伤是机械通气不可避免的缺点。ECMO可以长期替代和支持心肺功能,减少这种损伤的发生,并改善氧合。当重症腺病毒肺炎患者出现呼吸衰竭或ARDS,常规治疗未能改善低氧血症,或伴有漏气等并发症时,应考虑ECMO治疗。但国内相关研究较少,在重症腺病毒肺炎ECMO呼吸支持的呼吸支持模式选择、干预时机和管理要点等方面还需要进一步积累经验。关键词:体外膜肺氧合;严重腺病毒肺炎;呼吸支持
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期刊介绍: Chinese Journal of Neurology was established in 1955, the predecessor of which is Chinese Journal of Neurology and Psychiatry. Chinese Journal of Neurology and Psychiatry has been indexed by MEDLINE until 1996, when it was divided into two journals, Chinese Journal of Neurology, and Chinese Journal of Psychiatry. Chinese Journal of Neurology is now indexed by EM, SCOPUS, AJ, WPRIM, CNKI, Wanfang Data, CSCD, etc. The impact factor of the journal is 2.755 in 2017, ranking the first among all neurological and psychological journals in China and among all the 142 medical journals published by the Chinese Medical Association. The journal is available both in print and online.
期刊最新文献
The significance of pathogenic microorganism tests in infection determination Advances in the pathogenesis of severe adenovirus pneumonia in children The value and significance of imaging examination for infection and pathogen judgment Application of blood routine in the diagnosis of infectious diseases Preliminary determination of infection: clinical manifestations
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