Applications of Radiopharmaceuticals in the Treatment of Cancer: Recent Developments

R. Malviya, Priyanshi Goyal
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Abstract

An emerging safe and efficient targeted method of treating many different types of cancer is radiopharmaceutical treatment (RPT). RPT uses medications that either bind more selectively to cancer cells or accumulate through physiological processes to deliver radiation either systemically or locally. Nearly all radionuclides employed in RPT generate imageable photons, allowing for non-invasive visualization of the therapeutic agent's biodistribution. RPT has demonstrated efficacy with little toxicity when compared to practically all other systemic cancer treatment approaches. The tremendous potential of this treatment is finally being acknowledged as a result of the FDA's recent approval of many RPT medicines. The fundamental characteristics, clinical advancement, and related difficulties of RPT are covered in this review.
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放射性药物在癌症治疗中的应用:最新进展
一种新出现的安全有效的靶向治疗多种不同类型癌症的方法是放射性药物治疗(RPT)。RPT使用的药物要么更选择性地与癌症细胞结合,要么通过生理过程积累,以全身或局部传递辐射。RPT中使用的几乎所有放射性核素都会产生可成像光子,从而实现治疗剂生物分布的非侵入性可视化。与几乎所有其他系统性癌症治疗方法相比,RPT已证明其有效性和小毒性。由于美国食品药品监督管理局最近批准了许多RPT药物,这种治疗方法的巨大潜力终于得到了承认。本文综述了RPT的基本特征、临床进展和相关困难。
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来源期刊
CiteScore
1.00
自引率
0.00%
发文量
50
期刊介绍: Current Cancer Therapy Reviews publishes frontier reviews on all the latest advances in clinical oncology, cancer therapy and pharmacology. The journal"s aim is to publish the highest quality review articles dedicated to clinical research in the field. The journal is essential reading for all researchers and clinicians in cancer therapy.
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