Methodological aspects and prognostic value of metabolic tumor volume assessed with 18F-FDG PET/CT in lymphomas.

IF 1.5 4区 医学 Q3 PHARMACOLOGY & PHARMACY Current radiopharmaceuticals Pub Date : 2022-03-29 DOI:10.2174/1874471015666220329120631
F. Tutino, E. Giovannini, S. Pastorino, O. Ferrando, G. Giovacchini, A. Ciarmiello
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Abstract

Metabolic tumor volume (MTV) assessed by pretreatment 18F-FDG PET/CT has shown significant prognostic value across many lymphoma types, although not yet used in clinical practice for technical concerns and need for standardization. Numerous studies on the prognostic value of MTV in lymphomas have been published in recent years, but there is still no full agreement on the best methodology for MTV calculation. In this paper, we reviewed the methodological aspects of MTV assessment and reported recent works about its impact on outcome in lymphomas, with a focus on Hodgkin lymphoma (HL) and diffuse large B cell lymphoma (DLBCL).
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18F-FDG PET/CT评估淋巴瘤代谢肿瘤体积的方法学方面和预后价值。
通过预处理18F-FDG PET/CT评估的代谢肿瘤体积(MTV)在许多淋巴瘤类型中显示出显著的预后价值,尽管由于技术问题和标准化需求,尚未在临床实践中使用。近年来,关于MTV在淋巴瘤中的预后价值的许多研究已经发表,但对于MTV计算的最佳方法仍然没有完全一致。在本文中,我们回顾了MTV评估的方法学方面,并报道了其对淋巴瘤预后影响的最新工作,重点是霍奇金淋巴瘤(HL)和弥漫性大B细胞淋巴瘤(DLBCL)。
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来源期刊
Current radiopharmaceuticals
Current radiopharmaceuticals PHARMACOLOGY & PHARMACY-
CiteScore
3.20
自引率
4.30%
发文量
43
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