Evaluation of Frequency and Type of Severe Anemia in Patients Referred to the Baqiyatallah Hospital in Tehran in Six Months; A Descriptive Cross-Sectional Study

H. Jalalian, Meysam Shasti, Sadrollah Mahmoudi, H. Goodarzi
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Abstract

Purpose: To investigate the frequency and types of severe unknown anemia in patients referred to the Baqiyatallah Hospital (Tehran) for six months. Methods: In this descriptive cross-sectional study, the patients with severe unknown anemia referred to the Baqiyatallah Hospital (Tehran, Iran) were selected over six months. Following consideration of inclusion and exclusion criteria, 230 patients with severe anemia (hemoglobin (Hb) > 8gr/dl) were included. Complete medical history was obtained from the patients and additional biochemical blood analyses were applied to determine the frequency and type of anemia. SPSS (v.19) software was used to analyze the findings and the significance level was defined as a p-value <0.05. Results: In chronic disease anemia (47.5%), gastrointestinal bleeding-associated anemia (29%), bleeding malignancies anemia (21.5%), and aplastic anemia (2%). There were significant differences (p<0.05) in the frequency of different types of normocytic anemia. The highest frequency was detected in folate deficiency anemia (46%), hypothyroidism anemia (34%), and B12 deficiency anemia (20%), respectively. The hemolytic anemia represented a significant difference (p<0.05) in comparison with sickle cell anemia (95%). Also, sickle cell anemia showed a significant difference (p<0.05) between thalacemia-associated anemia (95%) and malignancy-related anemia (95%) Conclusion: Respectively, the highest frequency of anemia in patients was found in chronic diseases and gastrointestinal bleeding. It is suggested that more attention should be paid to the type of anemia of patients referred to the urgency of hospitals.
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德黑兰Baqiyatallah医院6个月内重症贫血患者频率和类型的评估一项描述性横断面研究
目的:调查在Baqiyatallah医院(德黑兰)转诊六个月的患者中发生严重不明贫血的频率和类型。方法:在这项描述性横断面研究中,选择在6个月内转诊至伊朗德黑兰Baqiyatallah医院的严重不明贫血患者。在考虑纳入和排除标准后,纳入了230名患有严重贫血(血红蛋白(Hb)>8gr/dl)的患者。从患者身上获得完整的病史,并应用额外的血液生化分析来确定贫血的频率和类型。SPSS(v.19)软件用于分析研究结果,显著性水平定义为p值<0.05。结果:慢性病性贫血(47.5%)、消化道出血性贫血(29%)、出血性恶性肿瘤性贫血(21.5%)和再生障碍性贫血(2%)。不同类型的正常细胞性贫血的发生率有显著差异(p<0.05)。叶酸缺乏性贫血(46%)、甲状腺功能减退性贫血(34%)和维生素B12缺乏性贫血症(20%)的发病率最高。溶血性贫血与镰状细胞性贫血(95%)相比有显著差异(p<0.05)。此外,镰状细胞性贫血在地中海贫血相关贫血(95%)和恶性肿瘤相关贫血(95%)之间显示出显著差异(p<0.05)。结论:慢性病和胃肠道出血分别是患者贫血的最高频率。建议应多注意贫血类型的患者转诊到医院的紧迫性。
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