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Support of Characteristics, Physical Environmental and Psychological On Quality Of Life Of Patients With DM Type II 特征、物理环境和心理对 II 型糖尿病患者生活质量的影响
Pub Date : 2024-07-15 DOI: 10.6000/1929-6029.2024.13.08
Fivit Febriani Malik, Ridwan Amiruddin, Wahiduddin Wahiduddin, I. L. Maria, Nurzakiah Hasan, Fridawaty Rivai, Haerani Haerani
Background: Diabetes mellitus is one of the diseases that ranks high in the list of non-communicable diseases in Indonesia. Factors that can affect quality of life such as physical environment and psychological. Objective: This study aims to examine the relationship between characteristic, physical environment and psychological on quality of life of type II diabetes mellitus patients at the Barombong Public Health Center, Makkasar City. Methodology: This study is a quantitative research with an analytical observational approach using a cross-sectional design. The population size in this study is 578 individuals, sample calculation using the WHO formula yielded a sample size of 385 individuals with predefined exclusion an inclusion criteria. The sampling technique employed is simple random sampling (SRS), and the hypothesis test used is chi-square. Results: Bivariate statistical analysis shows that there is a relationship between quality of life and age (p=0,000), duration of illness (p=0,000), temperature (p=0,000), noise (p=0,000), positive feelings (p=0,000), thinking, learning, and concentration (p=0,000), self-esteem (p=0,000), while variables that are not associated with quality of life are gender (p=0,111), marital status (p=0,228) and social support (p=0,645). Based on logistic regression analysis, it was found that the factors that most influence quality of life are duration of illness (p=0,000) and positive feelings (p=0,000). Conclusion: Length of suffering and positive feelings are the most dominant variables associated with quality of life with a probability level of 99.8%.
背景:糖尿病是印度尼西亚非传染性疾病中排名较高的疾病之一。影响生活质量的因素包括物理环境和心理因素。研究目的本研究旨在探讨 Makkasar 市 Barombong 公共卫生中心 II 型糖尿病患者的特征、物理环境和心理对其生活质量的影响。研究方法:本研究是一项定量研究,采用横断面设计的分析观察法。本研究的人口规模为 578 人,根据世界卫生组织的公式计算得出样本规模为 385 人,并预先确定了排除和纳入标准。采用的抽样技术是简单随机抽样(SRS),假设检验方法是卡方检验(chi-square)。结果双变量统计分析显示,生活质量与年龄(p=0,000)、病程(p=0,000)、温度(p=0,000)、噪音(p=0,000)、积极情绪(p=0,000)、思维、学习和注意力(p=0,000)、自尊(p=0,000)之间存在关系,而与生活质量无关的变量有性别(p=0,111)、婚姻状况(p=0,228)和社会支持(p=0,645)。根据逻辑回归分析,发现对生活质量影响最大的因素是病程(p=0,000)和积极情绪(p=0,000)。结论病程长短和积极情绪是与生活质量相关的最主要变量,概率水平为 99.8%。
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引用次数: 0
Competing Risks Model to Evaluate Dropout Dynamics Among the Type 1 Diabetes Patients Registered with the Changing Diabetes in Children (CDiC) Program 评估儿童糖尿病改变计划(CDiC)登记的 1 型糖尿病患者辍学动态的竞争风险模型
Pub Date : 2024-06-04 DOI: 10.6000/1929-6029.2024.13.06
Noora Al-Shanfari, Ronald Wesonga, Amadou Sarr, M. M. Islam
Understanding the survival dynamics of registered patients on a disease control program is a vital issue for the success of program objectives. Dropout of registered patients from such a program is a critical issue, hindering the effectiveness of the program. This study aimed to identify the risk factors of dropout of patients who were registered on the Changing Diabetes in Children (CDiC) program, taking a case of Uganda. Survival analysis was done by integrating competing risk of factors associated with attrition from the CDiC program. The data for the study was obtained from patients with type 1 diabetes mellitus (T1DM) registered during 2009-2018 at health units with specialized pediatric diabetes clinics from various regions in Uganda. The study considered follow-up data of 1132 children with T1DM. Our analysis revealed that the Body Mass Index (BMI) significantly influences dropout time, with patients classified as underweight showing higher hazards than those with normal BMI. Moreover, when considering competing risks, dropout hazards increased. Comparing the Cox model with the Fine and Gray model shows the latter exhibiting a smaller AIC value, which indicates its superiority in the time-to-dropout analysis. Thus, utilizing methods that integrate competing risks for CDiC dropout analysis is preferable and recommended for related studies. These findings provide actionable insights for enhancing CDiC program efficacy.
了解疾病控制计划注册患者的生存动态是计划目标能否成功实现的关键问题。注册患者退出此类项目是一个关键问题,会阻碍项目的有效性。本研究以乌干达为例,旨在确定儿童糖尿病改变计划(CDiC)注册患者辍学的风险因素。通过整合与 CDiC 计划流失相关的竞争风险因素,进行了生存分析。研究数据来自2009-2018年期间在乌干达各地区设有儿科糖尿病专科门诊的医疗单位登记的1型糖尿病(T1DM)患者。研究考虑了1132名1型糖尿病患儿的随访数据。我们的分析表明,体重指数(BMI)对辍学时间有显著影响,体重不足的患者比体重指数正常的患者有更高的风险。此外,如果考虑到竞争风险,辍学风险也会增加。将 Cox 模型与 Fine 和 Gray 模型进行比较后发现,后者的 AIC 值更小,这表明其在辍学时间分析中更具优势。因此,利用整合竞争风险的方法进行 CDiC 辍学分析是可取的,建议相关研究采用。这些发现为提高 CDiC 项目的有效性提供了可操作的见解。
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引用次数: 0
The Impact of the Risk Perception of COVID-19 PANDEMIC on College Students' Occupational Anxiety: The Moderating Effect of Career Adaptability COVID-19 PANDEMIC风险认知对大学生职业焦虑的影响:职业适应性的调节效应
Pub Date : 2024-05-21 DOI: 10.6000/1929-6029.2024.13.05
Jinhui Ning, Shi Yin, Ruonan Tang
In order to understand the changes in college students' risk perception and occupational emotion under major public health events and to explore the influencing factors of college graduates' employment guidance, 578 college students were surveyed by questionnaire to explore the impact of the risk perception of COVID-19 pandemic on college students' occupational anxiety and its internal mechanisms, and to analyze the mediating role of psychological resilience in the impact and the moderating role of career adaptability. The results showed that: (1) there is a significant positive correlation between the risk perception of COVID-19 pandemic and occupational anxiety; there is a significant negative correlation between risk perception and psychological resilience; there is a significant negative correlation between the psychological resilience and occupational anxiety. (2) Psychological resilience plays a mediating role between risk perception and occupational anxiety. (3) Career adaptability plays a negative moderating role between the risk perception of COVID-19 pandemic and occupational anxiety. These results showed that the risk perception of COVID-19 pandemic not only directly aggravates college students' occupational anxiety, but also indirectly affects occupational anxiety through psychological resilience; Career adaptability significantly alleviats the incremental effect of the risk perception of COVID-19 pandemic on college students' occupational anxiety. This paper has positive enlightenment on how to improve the employability of college students and alleviate their employment anxiety during major public health events.
为了解重大公共卫生事件下大学生风险认知与职业情绪的变化,探讨高校毕业生就业指导的影响因素,以578名大学生为对象,通过问卷调查的方式,探讨COVID-19大流行风险认知对大学生职业焦虑的影响及其内在机制,分析心理弹性在影响中的中介作用和职业适应性的调节作用。结果表明(1)COVID-19大流行风险认知与职业焦虑之间存在显著正相关;风险认知与心理复原力之间存在显著负相关;心理复原力与职业焦虑之间存在显著负相关。(2)心理复原力在风险认知与职业焦虑之间起中介作用。(3)职业适应性在 COVID-19 大流行风险感知与职业焦虑之间起负向调节作用。这些结果表明,COVID-19大流行病的风险认知不仅直接加重大学生的职业焦虑,还通过心理适应能力间接影响职业焦虑;职业适应能力显著缓解了COVID-19大流行病风险认知对大学生职业焦虑的递增效应。本文对在重大公共卫生事件中如何提高大学生就业能力、缓解大学生就业焦虑具有积极的启示意义。
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引用次数: 0
Adaptive Elastic Net on High-Dimensional Sparse Data with Multicollinearity: Application to Lipomatous Tumor Classification 具有多重共线性的高维稀疏数据的自适应弹性网:脂肪瘤分类应用
Pub Date : 2024-03-29 DOI: 10.6000/1929-6029.2024.13.04
N. Sudjai, Monthira Duangsaphon, Chandhanarat Chandhanayingyong
Predictive models can experience instabilities because of the combination of high-dimensional sparse data and multicollinearity problems. The adaptive Least Absolute Shrinkage and Selection Operator (adaptive Lasso) and adaptive elastic net were developed using the adaptive weight on penalty term. These adaptive weights are related to the power order of the estimators. Therefore, we concentrate on the power of adaptive weight on these penalty functions. This study purposed to compare the performances of the power of the adaptive Lasso and adaptive elastic net methods under high-dimensional sparse data with multicollinearity. Moreover, we compared the performances of the ridge, Lasso, elastic net, adaptive Lasso, and adaptive elastic net in terms of the mean of the predicted mean squared error (MPMSE) for the simulation study and the classification accuracy for a real-data application. The results of the simulation and the real-data application showed that the square root of the adaptive elastic net performed best on high-dimensional sparse data with multicollinearity.
由于高维稀疏数据和多重共线性问题的结合,预测模型可能会出现不稳定性。利用惩罚项的自适应权重,开发了自适应最小绝对收缩和选择操作符(自适应 Lasso)和自适应弹性网。这些自适应权重与估计器的幂级数有关。因此,我们将重点放在自适应权重对这些惩罚函数的影响上。本研究旨在比较自适应 Lasso 方法和自适应弹性网方法在具有多重共线性的高维稀疏数据下的幂级数性能。此外,我们还比较了脊法、拉索法、弹性网法、自适应拉索法和自适应弹性网法在模拟研究中的预测均方误差(MPMSE)平均值和真实数据应用中的分类准确率。模拟和真实数据应用的结果表明,自适应弹性网的平方根在具有多重共线性的高维稀疏数据中表现最佳。
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引用次数: 0
Triglyceridemic Waist Phenotypes as Risk Factors for Type 2 Diabetes Mellitus: A Systematic Review and Meta-Analysis 作为 2 型糖尿病风险因素的甘油三酯腰围表型:系统回顾和元分析
Pub Date : 2024-02-19 DOI: 10.6000/1929-6029.2024.13.03
Fiorella E. Zuzunaga-Montoya, V. Vera-Ponce
Introduction: Triglyceride waist phenotypes, which combine high triglyceride levels and central obesity, have recently emerged as an area of interest in metabolic disease research. Objective: To conduct a systematic review (SR) with meta-analysis to determine if triglyceride waist phenotypes are a risk factor for T2DM. Materials: SR with meta-analysis of cohort studies. The search was conducted in four databases: PubMed/Medline, Scopus, Web of Science, and EMBASE. Participants were classified into four groups, based on triglyceride level and waist circumference (WC): 1) Normal WC and normalConduct triglyceride level (NWNT); 2) Normal WC and high triglyceride level (NWHT), 3) Altered WC and normal triglyceride level (EWNT) and 4) Altered WC and high triglyceride level (EWHT). For the meta-analysis, only studies whose measure of association were presented as Hazard ratio (HR) along with 95% confidence intervals (CI95%) were used. Results: Compared to people with NWHT, a statistically significant association was found for those with NWHT (HR: 2.65; CI95% 1.77–3.95), EWNT (HR: 2.54; CI95% 2.05–3.16) and EWHT (HR: 4.41; CI95% 2.82–6.89). Conclusions: There is a clear association between triglyceride waist phenotypes and diabetes, according to this SR and meta-analysis. Although central obesity and high triglyceride levels are associated with a higher risk of the aforementioned disease, their combination appears to pose an even greater risk. Therefore, in the clinical setting, it is important to consider this when assessing the risk of diabetes.
简介:甘油三酯腰围表型是高甘油三酯水平和中心性肥胖的结合,最近已成为代谢性疾病研究的一个关注领域。研究目的通过荟萃分析进行系统综述(SR),以确定甘油三酯腰围表型是否是 T2DM 的风险因素。材料:对队列研究进行系统综述和荟萃分析。在四个数据库中进行了检索:PubMed/Medline、Scopus、Web of Science 和 EMBASE。根据甘油三酯水平和腰围将参与者分为四组:1)正常腰围和正常甘油三酯水平(NWNT);2)正常腰围和高甘油三酯水平(NWHT);3)改变腰围和正常甘油三酯水平(EWNT);4)改变腰围和高甘油三酯水平(EWHT)。在进行荟萃分析时,只使用了以危险比(HR)和 95% 置信区间(CI95%)表示相关性的研究。结果与 NWHT 患者相比,NWHT(HR:2.65;CI95% 1.77-3.95)、EWNT(HR:2.54;CI95% 2.05-3.16)和 EWHT(HR:4.41;CI95% 2.82-6.89)患者的相关性具有统计学意义。结论根据该 SR 和荟萃分析,甘油三酯腰围表型与糖尿病之间存在明显的关联。虽然中心性肥胖和高甘油三酯水平与上述疾病的高风险有关,但两者结合似乎会带来更大的风险。因此,在临床环境中,评估糖尿病风险时必须考虑到这一点。
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引用次数: 0
Advancing Healthcare Service Efficacy by Optimizing Pharmaceutical Inventory Management: Leveraging ABC, VED Analysis for Trend Demand 通过优化药品库存管理提高医疗保健服务效率:利用 ABC 和 VED 分析了解需求趋势
Pub Date : 2023-12-28 DOI: 10.6000/1929-6029.2023.12.33
G. Umadevi, S. Umamaheswari
Background: The modern world has witnessed significant advancements across various industries such as food, healthcare, fashion, economics, and education. Among these sectors, healthcare is essential, given its critical role in promoting the well-being of individuals and communities. Purpose: Pharmaceuticals are a significant part of the healthcare system, as they are a crucial factor in increasing life expectancy and are often considered the heart of the health industry. Maintaining effective inventory management for drugs is essential for pharmacists to provide efficient and reliable services to their patients. Methodology: The study thoroughly analyzes the cost and consumption data for each type of demand, to develop a well-suited review and issuance policy for the apothecary. Research Limitations/Implications: The paper delves into the ABC analysis, VED analysis, and trend demand for medical stores, making it a valuable resource for pharmacy stores seeking to optimize their operations and inventory management. Originality/Value: A total of 564 drugs were included in this study, and data were collected from random strip sales between October 2022 and Mar 2023. The study's findings can be used to make informed decisions about inventory planning and classification strategies. The model utilized in this study is based on three categories of medicines: high priority, medium priority, and low priority. By analyzing the demand for these medicines, they can be categorized based on their priority within the three core groups. Pharmacists can use the model to detect shortages and take proactive measures to avoid them by analyzing demand patterns and inventory levels.
背景:当今世界,食品、医疗保健、时尚、经济和教育等各行各业都取得了长足的进步。在这些行业中,医疗保健至关重要,因为它在促进个人和社区福祉方面发挥着关键作用。 目的:药品是医疗保健系统的重要组成部分,因为药品是延长预期寿命的关键因素,通常被视为医疗保健行业的核心。药剂师要为患者提供高效可靠的服务,就必须对药品进行有效的库存管理。 研究方法:本研究深入分析了各类需求的成本和消耗数据,为药剂师制定了一套完善的审查和发放政策。 研究局限性/意义:本文深入分析了医药商店的 ABC 分析、VED 分析和趋势需求,为药店优化运营和库存管理提供了宝贵的资源。 原创性/价值:本研究共涉及 564 种药品,数据来自 2022 年 10 月至 2023 年 3 月期间的随机带状销售。研究结果可用于就库存规划和分类策略做出明智决策。本研究采用的模型基于三类药品:高优先级、中优先级和低优先级。通过分析这些药品的需求量,可以根据其在三个核心类别中的优先级对其进行分类。药剂师可利用该模型检测短缺情况,并通过分析需求模式和库存水平采取积极措施避免短缺。
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引用次数: 0
Analysis of the Effectiveness of Periodontitis Treatment Using Antimicrobial Agents 使用抗菌剂治疗牙周炎的效果分析
Pub Date : 2023-12-19 DOI: 10.6000/1929-6029.2023.12.30
Oleksandr Korniichuk, Vasyl Humeniuk, Olha Isakova, Borys Shchepanskyi, Vasyl Antoniv
A combination of systemic antibiotics with scaling may provide an additional advantage over scaling alone in the periodontitis treatment in terms of clinical loss of attachment and change in pocket depth. The use of antibiotics should be justified by a determined need and should not replace adequate local treatment. Different treatment protocols have been proposed, but their indications and efficacy remain controversial. The study aims to analyse the literature on the use of antimicrobial agents for non-surgical periodontal therapy and to compare different protocols for prescribing antimicrobial agents. A search in MEDLINE and EBSCOhost electronic databases was conducted using relevant MeSH words. Targeted studies had to be published within the last five years. Studies were selected based on inclusion and exclusion criteria. Data from selected studies were extracted and analysed. Ten randomized clinical trials were included in the review. The general conclusions of this review indicate a positive effect of antibiotics as an adjunct to non-surgical treatment of chronic periodontitis, regardless of antimicrobial drugs used in the reviewed studies. A prospect for further research is a comparative analysis of the effectiveness of the use of antimicrobial agents and probiotics as an adjunct to the non-surgical treatment of chronic periodontitis.
在牙周炎的治疗中,系统性抗生素与洗牙相结合,在临床附着丧失和牙周袋深度变化方面可能比单独洗牙更有优势。抗生素的使用应根据确定的需要,不应取代适当的局部治疗。目前已经提出了不同的治疗方案,但其适应症和疗效仍存在争议。本研究旨在分析有关在非手术牙周治疗中使用抗菌剂的文献,并比较不同的抗菌剂处方方案。我们使用相关的 MeSH 词在 MEDLINE 和 EBSCOhost 电子数据库中进行了检索。目标研究必须是在过去五年内发表的。根据纳入和排除标准对研究进行筛选。对所选研究的数据进行提取和分析。十项随机临床试验被纳入综述。本综述的总体结论表明,无论综述研究中使用何种抗菌药物,抗生素作为慢性牙周炎非手术治疗的辅助手段都有积极作用。进一步研究的前景是对使用抗菌药物和益生菌作为慢性牙周炎非手术治疗的辅助手段的效果进行比较分析。
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引用次数: 0
The Effect of Symptoms on the Survival Time of Coronavirus Patients in the Sudanese Population 症状对苏丹人口中冠状病毒患者存活时间的影响
Pub Date : 2023-12-19 DOI: 10.6000/1929-6029.2023.12.29
A. A. Shokeralla, M. E. Qurashi, Reem Yousif Mekki, Mortada S. Ali
The COVID-19 pandemic has rapidly spread worldwide, resulting in substantial rates of illness and death. Gaining insight into the various factors that impact the duration of survival among individuals diagnosed with COVID-19 is of utmost importance to inform clinical practices and public health strategies This study aims to evaluate the relationship between the acuteness of symptoms and the survival time of coronavirus patients in Sudan. The Kaplan-Meier curves and log-rank test were used to determine the symptom pattern. The results of COVID-19 and Cox regression were utilized to determine the most critical symptoms affecting coronavirus patients. The log-rank test revealed that there are differences in the pattern of age and symptoms among coronavirus patients. Cox regression revealed that symptoms affect on the survival time of coronavirus patients. The Cox proportional Hazard Model shows that the hazard of age at any time increases by 116.5%, diarrhea increases by 9%, headache increases by 62.0%, fatigability increases by 13.3%, and other symptoms increase by 47.3%. This study differs from prior studies in several ways. No current study in Sudan has used survival analysis to discover the most relevant symptoms affecting survival time.
COVID-19 大流行在全球迅速蔓延,导致大量患者患病和死亡。本研究旨在评估苏丹冠状病毒患者的症状严重程度与存活时间之间的关系。研究采用 Kaplan-Meier 曲线和对数秩检验来确定症状模式。利用 COVID-19 和 Cox 回归的结果来确定影响冠状病毒患者的最关键症状。对数秩检验显示,冠状病毒患者的年龄和症状模式存在差异。Cox 回归显示,症状会影响冠状病毒患者的生存时间。Cox 比例危险度模型显示,任何时间的年龄危险度增加 116.5%,腹泻危险度增加 9%,头痛危险度增加 62.0%,疲劳危险度增加 13.3%,其他症状危险度增加 47.3%。这项研究与之前的研究有几处不同。目前在苏丹进行的任何研究都没有使用生存分析来发现影响生存时间的最相关症状。
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引用次数: 0
The Role of Emotional Intelligence in the Rehabilitation of the Former Prisoners of War 情商在前战俘康复中的作用
Pub Date : 2023-12-14 DOI: 10.6000/1929-6029.2023.12.28
Yevhenii Ishchenko, Yuliia Chystovska, Olga Vovchenko, Inesa Harkusha, Hanna Voshkolup
The emotional state of military personnel engaged in the extensive operations taking place in Ukraine is undoubtedly impacted. This especially applies to former prisoners of war (POWs) who have experienced mental and physical trauma. Optimizing their subjective well-being and life satisfaction can contribute to the development of emotional intelligence during the rehabilitation process. The purpose of the study is to identify the importance of emotional intelligence in enhancing the subjective well-being of former POWs. Methods. The following psychometric tests were used for diagnosis: EQ-Test, the Scale of subjective well-being, and Satisfaction with life scale (SWLS). During the statistical analysis, descriptive statistics and correlation analysis were utilized. Results. The study found that the subjects have low emotional intelligence (M=39.31, SD=12.85), low subjective well-being (M=50.19, SD=11.06), and an average level of life satisfaction (M= 17.05, SD=8.96). Correlation analysis established a direct relationship between emotional intelligence and subjective well-being (r=0.483, p≤0.01) and life satisfaction (r=0.723, p≤0.01). Conclusions. The study statistically confirmed that emotional intelligence is an essential factor in the process of rehabilitation of former prisoners of war, as it contributes to their attainment of subjective well-being and life satisfaction. This aids in reinstating the individual's psychological balance after captivity, enhances the medical and physical recuperation process of the body, and ensures full reintegration. Prospects. The obtained results contribute to the rehabilitation system of rehabilitation for former prisoners of war, as they elaborate a comprehensive emotional intelligence approach to ensure their subjective well-being and life satisfaction.
参与乌克兰大规模行动的军事人员的情绪无疑会受到影响。这尤其适用于经历过身心创伤的前战俘(POW)。优化他们的主观幸福感和生活满意度有助于在康复过程中发展情商。本研究旨在确定情商在提高前战俘主观幸福感方面的重要性。研究方法采用以下心理测试进行诊断:情商测试、主观幸福感量表和生活满意度量表(SWLS)。在统计分析过程中,使用了描述性统计和相关分析。研究结果研究发现,受试者的情商较低(M=39.31,SD=12.85),主观幸福感较低(M=50.19,SD=11.06),生活满意度一般(M=17.05,SD=8.96)。相关分析表明,情商与主观幸福感(r=0.483,p≤0.01)和生活满意度(r=0.723,p≤0.01)之间存在直接关系。结论研究从统计学角度证实,情商是前战俘康复过程中的一个重要因素,因为它有助于他们获得主观幸福感和生活满意度。这有助于恢复个人被俘后的心理平衡,加强医疗和身体康复过程,确保完全重新融入社会。展望未来。所取得的成果有助于退役战俘的康复系统,因为它们阐述了一种全面的情商方法,以确保他们的主观幸福感和生活满意度。
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引用次数: 0
Comparative Study on Estimation Methods of Proportional Hazard Models for Interval-Censored Data 区间删失数据的比例危险模型估计方法比较研究
Pub Date : 2023-12-13 DOI: 10.6000/1929-6029.2023.12.27
Sonobe Keita, Asanao Shimokawa, Etsuo Miyaoka
Purpose: In this study, we compare the estimation methods of interval-censored data using both simulated and real data. Many past studies have used fixed sample sizes in their simulation studies. We performed the best possible simulation study. Method: The methods include Finkelstein’s method with Piecewise and Spline and imputation methods (i.e., Efron’s method in the Cox model). Results: If the interval-censored data do not overlap, the same estimation results are obtained regardless of the assignment point for the estimation of the Cox model. The overlapping data also did not significantly affect the accuracy of the estimation. On the other hand, Finkelstein’s method showed differences in estimation depending on the two estimation methods of the baseline survival function. Although it was not possible to determine which method had better power, the Spline method had a smaller absolute error than the Finkelstein method. A comparison of Cox’s and Finkelstein’s methods showed that Finkelstein’s method was superior in terms of power. Conclusion: Interval-censored data is a form of data that can be found in a variety of fields. In this study, we compared estimation methods for interval-censored data, and the usefulness of Finkelstein’s method can be seen from simulation studies.
目的:在本研究中,我们使用模拟数据和真实数据对区间删失数据的估计方法进行了比较。过去的许多研究在模拟研究中都使用了固定的样本量。我们进行了尽可能好的模拟研究。方法:方法包括使用片断法和样条法的 Finkelstein 方法以及估算方法(即 Cox 模型中的 Efron 方法)。结果:如果区间删失数据没有重叠,则无论采用哪种赋值点对 Cox 模型进行估计,都能得到相同的估计结果。重叠数据也不会对估计的准确性产生重大影响。另一方面,Finkelstein 方法显示,基线生存函数的两种估计方法在估计结果上存在差异。虽然无法确定哪种方法更有效,但 Spline 方法的绝对误差小于 Finkelstein 方法。对 Cox 方法和 Finkelstein 方法进行比较后发现,Finkelstein 方法在功率方面更胜一筹。结论区间删失数据是一种数据形式,可以在各种领域中找到。在本研究中,我们比较了区间删失数据的估计方法,从模拟研究中可以看出 Finkelstein 方法的实用性。
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引用次数: 0
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International journal of statistics in medical research
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