Active music therapy in dementia: results from an open-label trial

Mariângela Aparecida Rezende Aleixo, M. B. Borges, Bruno Rabinovici Gherman, I. Teixeira, José Pedro Simões Neto, R. Santos, M. Dourado, V. Marinho
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Abstract

ABSTRACT Objective: Cognitive, neuropsychiatric and functional deficits are core symptoms of dementia. Non-pharmacological interventions, such as music therapy, when used in conjunction with pharmacological treatment, have the potential to alleviate these symptoms. The purpose of this preliminary study is to examine the active music therapy on cognition and neuropsychiatric symptoms in the elderly with mild and moderate dementia. Methods: The initial sample consisted of outpatients with dementia (N = 15) and their family members or caregivers (N = 15). Two dyads did not complete the assessments before intervention and were excluded from the analysis. Thirteen females (N = 13) comprised the final sampled and were diagnosed with Alzheimer’s disease (N = 10), vascular dementia (N = 2) and mixed dementia (N = 1), at mild (N = 11) and moderate (N = 2) dementia stage. Participants were enrolled in an open-label trial of active music therapy group, set to take place once weekly for 60 minutes over a period of 12 weeks. Results: Participants experienced a slight improvement on cognition measured with Mini-Mental State Examination (p = 0.41), although without statistical significance and a statistically significant decrease in anxiety (p = 0.042) in post-intervention. There were no significant effects on quality of life and caregiver burden. Conclusions: Active music therapy is a promising intervention with good acceptance among participants. More studies with larger sample sizes are needed to confirm its effects and efficacy in cognitive and neuropsychiatric symptoms in dementia.
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积极音乐治疗痴呆:一项开放标签试验的结果
摘要目的:认知、神经精神和功能障碍是痴呆的核心症状。非药物干预措施,如音乐疗法,与药物治疗结合使用时,有可能减轻这些症状。本初步研究的目的是探讨积极音乐疗法对老年轻中度痴呆患者认知和神经精神症状的影响。方法:初始样本为门诊痴呆患者(N = 15)及其家属或照顾者(N = 15)。有两对在干预前没有完成评估,因此被排除在分析之外。13名女性(N = 13)组成了最终的样本,在轻度(N = 11)和中度(N = 2)痴呆阶段被诊断为阿尔茨海默病(N = 10)、血管性痴呆(N = 2)和混合性痴呆(N = 1)。参与者参加了一个开放标签的积极音乐治疗组的试验,每周进行一次,每次60分钟,持续12周。结果:干预后,参与者的认知能力有轻微改善(p = 0.41),但没有统计学意义,焦虑程度有统计学意义的降低(p = 0.042)。对生活质量和照顾者负担没有显著影响。结论:积极音乐治疗是一种很有前途的干预方法,在参与者中有很好的接受度。需要更多样本量更大的研究来证实其对痴呆患者认知和神经精神症状的影响和疗效。
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来源期刊
Jornal Brasileiro de Psiquiatria
Jornal Brasileiro de Psiquiatria Medicine-Psychiatry and Mental Health
CiteScore
1.30
自引率
0.00%
发文量
26
审稿时长
20 weeks
期刊介绍: O Jornal Brasileiro de Psiquiatria se insere em programas de educação continuada e atualização e tem como missão divulgar trabalhos de pesquisa (realizados em instituições brasileiras e estrangeiras) cujos resultados tenham potencial para a investigação e prática clínica no campo da Psiquiatria. Criado em 1938, foi publicado até 1950, sob o título “Anais do Instituto de Psiquiatria”, sem periodicidade regular.
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