Chromatographic Fractionation of An Ethanolic Extract of Peels from Ipomoea batatas Lam for Improved Anticancer Activity

Abstract

In this current work, the n-hexane fraction from an ethanolic extract of pulverized peel of Ipomoea batatas Lam was subjected to chromatographic fractionation. Consequently, the fractions were investigated for their anticancer potential using the Sulforhodamine-B assay. Chromatographic fractionation led to n-hexane sub-fractions with greater anticancer potential. The study highlights the peel of Ipomoea batatas Lam as a rich dietary source of natural anticancer molecules which may be developed into nutraceuticals or serve as new leads in anticancer therapy. Keywords: Ipomoea batatas; Chromatography; Fractionation; Anticancer; Sulforhodamine-B