{"title":"The pathogenic roles of lncRNAs in glioma","authors":"M. Farzaneh, Arya Moftakhar, S. Khoshnam","doi":"10.2174/1573394719666230316112549","DOIUrl":null,"url":null,"abstract":"\n\nBrain cancers or intracranial cancers are among the deadliest cancers in the world. The presence of tumorigenic cancer cells in the brain and induction of poor prognosis may impact the survival/death balance. Glioma is a type of brain tumor that begins in the glial tissue. Recently, it has been reported that long non-coding RNAs (lncRNAs) with at least 200 nucleotides in length by targeting DNAs, RNAs, and proteins play essential roles in several biological processes, including growth, differentiation, and development. Recently, lncRNAs was reported to contribute to the tumorigenesis of glioma by targeting miRNAs, other ncRNAs, and mRNAs. In this review, we focused on the functional roles of lnRNAs in glioma.\n","PeriodicalId":43754,"journal":{"name":"Current Cancer Therapy Reviews","volume":" ","pages":""},"PeriodicalIF":0.4000,"publicationDate":"2023-03-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Current Cancer Therapy Reviews","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.2174/1573394719666230316112549","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q4","JCRName":"ONCOLOGY","Score":null,"Total":0}
引用次数: 0
Abstract
Brain cancers or intracranial cancers are among the deadliest cancers in the world. The presence of tumorigenic cancer cells in the brain and induction of poor prognosis may impact the survival/death balance. Glioma is a type of brain tumor that begins in the glial tissue. Recently, it has been reported that long non-coding RNAs (lncRNAs) with at least 200 nucleotides in length by targeting DNAs, RNAs, and proteins play essential roles in several biological processes, including growth, differentiation, and development. Recently, lncRNAs was reported to contribute to the tumorigenesis of glioma by targeting miRNAs, other ncRNAs, and mRNAs. In this review, we focused on the functional roles of lnRNAs in glioma.
期刊介绍:
Current Cancer Therapy Reviews publishes frontier reviews on all the latest advances in clinical oncology, cancer therapy and pharmacology. The journal"s aim is to publish the highest quality review articles dedicated to clinical research in the field. The journal is essential reading for all researchers and clinicians in cancer therapy.