{"title":"Application value of fecal calprotectin in necrotizing enterocolitis","authors":"Jinglin Xu, Bin Wu","doi":"10.3760/CMA.J.ISSN.1673-4912.2019.09.011","DOIUrl":null,"url":null,"abstract":"Necrotizing enterocolitis(NEC)is the most important gastrointestinal emergency of preterm neonates in neonatal intensive care units.The diagnosis of NEC is difficult during its earliest stages.Looking for all early specific biological indicators to recognize cases during its earliest stages is important.Fecal calprotectin, as a simple and noninvasive test index, has been widely used in inflammatory diseases in adults and children.Studies have shown that fecal calprotectin is significantly higher in newborns with NEC, which can be used as an screening marker for the detection of NEC or an indicator to predict the occurrence and severity of the disease.This review summarized the characteristics of fecal calprotectin in neonates and its clinical significance as a noninvasive marker of necrotizing enterocolitis. \n \n \nKey words: \nCalprotectin; Necrotizing enterocolitis; Infant, newborn","PeriodicalId":68901,"journal":{"name":"中国小儿急救医学","volume":"26 1","pages":"691-695"},"PeriodicalIF":0.0000,"publicationDate":"2019-09-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"中国小儿急救医学","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.3760/CMA.J.ISSN.1673-4912.2019.09.011","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 0
Abstract
Necrotizing enterocolitis(NEC)is the most important gastrointestinal emergency of preterm neonates in neonatal intensive care units.The diagnosis of NEC is difficult during its earliest stages.Looking for all early specific biological indicators to recognize cases during its earliest stages is important.Fecal calprotectin, as a simple and noninvasive test index, has been widely used in inflammatory diseases in adults and children.Studies have shown that fecal calprotectin is significantly higher in newborns with NEC, which can be used as an screening marker for the detection of NEC or an indicator to predict the occurrence and severity of the disease.This review summarized the characteristics of fecal calprotectin in neonates and its clinical significance as a noninvasive marker of necrotizing enterocolitis.
Key words:
Calprotectin; Necrotizing enterocolitis; Infant, newborn
期刊介绍：
Chinese Journal of Neurology was established in 1955, the predecessor of which is Chinese Journal of Neurology and Psychiatry. Chinese Journal of Neurology and Psychiatry has been indexed by MEDLINE until 1996, when it was divided into two journals, Chinese Journal of Neurology, and Chinese Journal of Psychiatry. Chinese Journal of Neurology is now indexed by EM, SCOPUS, AJ, WPRIM, CNKI, Wanfang Data, CSCD, etc. The impact factor of the journal is 2.755 in 2017, ranking the first among all neurological and psychological journals in China and among all the 142 medical journals published by the Chinese Medical Association. The journal is available both in print and online.
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