Laparoscopic Splenectomy in Non-Cirrhotic Portal Hypertension- A Retrospective Analysis of a Prospectively Performed Series

J. Aluru
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Abstract

In our institute, laparoscopic splenectomy was performed in 27 patients over a period of 7 years for two major indications: hypersplenism and refractory variceal bleeding. 19 patients had Extra Hepatic Portal Venous Obstruction (EHPVO) and 8 patients had Non-Cirrhotic Portal Fibrosis ( NCPF). All the patients had hypersplenism, with thrombocytopenia( < 50,000/cu.mm),leukopenia (< 4000/Cu mm)as well in 9 (33% )of the patients, and anemia ( Hb<10gm) in 8(30%) . Variceal bleeding requiring Endoscopic Variceal Ligation (EVL) were found in 23 patients,17 in the EHPVO group and 6 in the NCPF group . 4 patients were females and 23 were male. The age range was from 12 to 37 years, the mean being 24 years. The laparoscopic procedure was successful in 25, but 2 patients needed conversion to left subcostal laparotomy because of extensive and giant collaterals around the hilum of the spleen; these conversions happened in the first three years of our laparoscopic splenectomy experience, with no conversions in the subsequent 4 years. Even in the presence of a relative contraindication like portal hypertension, laparoscopic splenectomy is still a viable proposition in the vast majority of cases. Technical considerations , like deployment of powerful energy sources, vascular staplers and preliminary splenic artery ligation are discussed in this article.
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腹腔镜脾切除术治疗非肝硬化门脉高压症——前瞻性系列手术的回顾性分析
在我们的研究所,27名患者在7年的时间里进行了腹腔镜脾切除术,主要有两个适应症:脾功能亢进和难治性静脉曲张出血。肝外门静脉阻塞(EHPVO)19例,非肝硬化门脉纤维化(NCPF)8例。所有患者都有脾功能亢进,9例(33%)患者出现血小板减少症(<50000/cu.mm)、白细胞减少症(<4000/cu.mm),8例(30%)患者出现贫血(Hb<10gm)。23例患者出现需要内镜下静脉曲张结扎术(EVL)的静脉曲张出血,EHPVO组17例,NCPF组6例。女性4例,男性23例。年龄范围从12岁到37岁,平均24岁。腹腔镜手术成功25例,但2例患者由于脾门周围有大量巨大的络脉,需要转为左侧肋下剖腹手术;这些转化发生在我们腹腔镜脾切除术经验的前三年,在随后的4年中没有转化。即使存在门静脉高压等相对禁忌症,腹腔镜脾切除术在绝大多数病例中仍然是可行的。本文讨论了技术上的考虑,如部署强大的能源,血管缝合器和初步脾动脉结扎。
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