{"title":"Progress of extracellular vesicle and its microRNA in multiple myeloma","authors":"Xu Lu","doi":"10.3760/CMA.J.ISSN.1006-9801.2019.12.018","DOIUrl":null,"url":null,"abstract":"Multiple myeloma (MM) is a common disease in the blood system, which mostly occurs in the middle-aged and the senior people. The pathogenesis of MM is not clear and MM can not be completely cured at present. Recent studies have found that microRNA (miRNA) plays a key role in the occurrence and development of MM. In addition, MM cells can release extracellular vesicle (EV), and involve in the intercellular information transmission and regulation. This paper reviews the role of EV in the development of MM. Key words: Multiple myeloma; Extracellular vesicle; Exosomes; MicroRNAs","PeriodicalId":9505,"journal":{"name":"肿瘤研究与临床","volume":null,"pages":null},"PeriodicalIF":0.0000,"publicationDate":"2019-12-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"肿瘤研究与临床","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.3760/CMA.J.ISSN.1006-9801.2019.12.018","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q4","JCRName":"Medicine","Score":null,"Total":0}
引用次数: 0
Abstract
Multiple myeloma (MM) is a common disease in the blood system, which mostly occurs in the middle-aged and the senior people. The pathogenesis of MM is not clear and MM can not be completely cured at present. Recent studies have found that microRNA (miRNA) plays a key role in the occurrence and development of MM. In addition, MM cells can release extracellular vesicle (EV), and involve in the intercellular information transmission and regulation. This paper reviews the role of EV in the development of MM. Key words: Multiple myeloma; Extracellular vesicle; Exosomes; MicroRNAs
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