Cognitive Impairment Secondary to Treatment of Cured Brain Metastases of Triple-Negative Breast Carcinoma

Oncogen Pub Date : 2019-05-02 DOI:10.35702/ONC.10011
E. Nassif, A. Arsène-Henry, Y. Kirova
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Abstract

Materials and methods: We report the case of a 58 years old women cured of brain metastases from TNBC. Initial diagnosis was of locally advanced inflammatory TNBC for which the patient underwent high-dose neo-adjuvant chemotherapy followed by surgery, radiotherapy and adjuvant chemotherapy. Symptomatic brain metastases were diagnosed 10 months after the end of adjuvant chemotherapy. Whole-brain radiotherapy and stereotactic radiosurgery were rapidly delivered followed by twelve months of chemotherapy.
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三阴性乳腺癌脑转移治愈后继发认知障碍的研究
材料与方法:我们报告一例58岁女性三阴癌脑转移瘤治愈病例。初步诊断为局部晚期炎性TNBC,患者接受大剂量新辅助化疗,随后手术、放疗和辅助化疗。在辅助化疗结束10个月后诊断出症状性脑转移。全脑放疗和立体定向放射手术在12个月的化疗后迅速进行。
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