Mucormycosis - A Rare, yet Lethal Infection: A Review

IF 0.2 Q4 Biochemistry, Genetics and Molecular Biology Research Journal of Biotechnology Pub Date : 2022-10-25 DOI:10.25303/1711rjbt1270135
Arvind Sethuraman Vairavan Charles, Naveed Sohaira, Ala Sidheeq Aminath, Anthonette Nivetha Sethu Raman Vairavan Christina, Suryadevara Nagaraja
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Abstract

Mucormycosis is an angio invasive infection caused by Mucorales fungi, which is mostly observed in diabetic and immunocompromised patients. The infection can be classified into cutaneous, rhino-orbito cerebral, gastrointestinal, disseminated and other rare pulmonary types. The overall mortality rate due to this infection has increased, even with aggressive treatment. Moreover, there has been a major mucormycosis outbreak in India following the deadly second wave of COVID-19 cases in the country. The epidemiology of mucormycosis is evolving due to advances in therapeutics and early diagnostics tools. The aim of this review is to provide an overview of the epidemiology, pathogenesis and types of mucormycosis along with an update on the recent advanced diagnostics tools and therapeutics to combat the rare, yet lethal infection.
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毛霉病——一种罕见但致命的感染:综述
毛霉菌病是一种由毛霉菌引起的血管侵袭性感染,主要见于糖尿病和免疫功能低下的患者。感染可分为皮肤型、鼻-眶-脑型、胃肠型、播散型和其他罕见的肺部类型。即使进行了积极的治疗,这种感染导致的总体死亡率也有所上升。此外,在印度出现致命的第二波新冠肺炎病例后,印度爆发了大规模毛霉菌病疫情。由于治疗学和早期诊断工具的进步,毛霉菌病的流行病学正在发展。这篇综述的目的是概述毛霉菌病的流行病学、发病机制和类型,以及最新的先进诊断工具和治疗方法,以对抗这种罕见但致命的感染。
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来源期刊
Research Journal of Biotechnology
Research Journal of Biotechnology 工程技术-生物工程与应用微生物
CiteScore
0.60
自引率
0.00%
发文量
192
审稿时长
1.5 months
期刊介绍: We invite you to contribute Research Papers / Short Communications / Review Papers: -In any field of Biotechnology, Biochemistry, Microbiology and Industrial Microbiology, Soil Technology, Agriculture Biotechnology. -in any field related to Food Biotechnology, Nutrition Biotechnology, Genetic Engineering and Commercial Biotechnology. -in any field of Biotechnology related to Drugs and Pharmaceutical products for human beings, animals and plants. -in any field related to Environmental Biotechnolgy, Waste Treatment of Liquids, Soilds and Gases; Sustainability. -in inter-realted field of Chemical Sciences, Biological Sciences, Environmental Sciences and Life Sciences. -in any field related to Biotechnological Engineering, Industrial Biotechnology and Instrumentation. -in any field related to Nano-technology. -in any field related to Plant Biotechnology.
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