Side Effects of Long - Term Glucocorticoid Therapy: Case Report

Ioana-Codruța Lebădă, Elena Teodora Măerean, Roxana-Florina Ință
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Abstract

Abstract Glucocorticoids are one of the most common classes of drugs used to treat a diverse variety of inflammatory and autoimmune disorders. Despite their effects, long-term therapy exposes patients to multiple side effects, such as weight gain, high blood pressure, adrenal insufficiency, osteoporosis and a high risk of infections. We present the case of a 61-year-old female with osteoporosis secondary to glucocorticoid therapy, adrenal insufficiency, new-onset diabetes mellitus and mixed dyslipidemia, manifestations that occurred as a result of self-administration of Medrol for one year. The patient presented to the hospital for thoracic back pain, being sent to the endocrinologist due to radiological changes suggestive of vertebral compressions.
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长期糖皮质激素治疗的副作用:病例报告
摘要糖皮质激素是最常见的一类药物,用于治疗各种炎症和自身免疫性疾病。尽管有效果,但长期治疗会使患者面临多种副作用,如体重增加、高血压、肾上腺功能不全、骨质疏松和感染风险高。我们报告了一例61岁女性骨质疏松症,继发于糖皮质激素治疗、肾上腺功能不全、新发糖尿病和混合性血脂异常,这些表现是由于自我给药一年而出现的。患者因胸部背痛被送往医院,由于放射学变化提示脊椎按压,被送往内分泌科。
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