{"title":"Progress in humoral immunity of mature B-cell non-Hodgkin lymphoma in children","authors":"Meng Zhang, N. Zhang, Xiao-li Ma","doi":"10.3760/CMA.J.ISSN.1673-419X.2019.02.015","DOIUrl":null,"url":null,"abstract":"Mature B-cell non-Hodgkin lymphoma (B-NHL) is a common malignant tumor in children. In recent years, with the development of tumor immunology, immunotherapy has become a hot spot, and the changes of humoral immunity levels before and after treatment have attracted more attention. This article reviews the issues of humoral immunity before chemotherapy in children with B-NHL, the effect of chemotherapy on humoral immunity in children, and the latest research progress. \n \n \nKey words: \nB-lymphocytes; Lymphoma, non-Hodgkin; Immunity, humoral; Immunoglobulin A; Immunoglobulin G; Immunoglobulin M","PeriodicalId":13774,"journal":{"name":"国际输血及血液学杂志","volume":"42 1","pages":"170-174"},"PeriodicalIF":0.0000,"publicationDate":"2019-03-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"国际输血及血液学杂志","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.3760/CMA.J.ISSN.1673-419X.2019.02.015","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 0
Abstract
Mature B-cell non-Hodgkin lymphoma (B-NHL) is a common malignant tumor in children. In recent years, with the development of tumor immunology, immunotherapy has become a hot spot, and the changes of humoral immunity levels before and after treatment have attracted more attention. This article reviews the issues of humoral immunity before chemotherapy in children with B-NHL, the effect of chemotherapy on humoral immunity in children, and the latest research progress.
Key words:
B-lymphocytes; Lymphoma, non-Hodgkin; Immunity, humoral; Immunoglobulin A; Immunoglobulin G; Immunoglobulin M
期刊介绍：
The International Journal of Transfusion and Hematology was founded in September 1978. It is a comprehensive academic journal in the field of transfusion and hematology, supervised by the National Health Commission and co-sponsored by the Chinese Medical Association, West China Second Hospital of Sichuan University, and the Institute of Transfusion Medicine of the Chinese Academy of Medical Sciences. The journal is a comprehensive academic journal that combines the basic and clinical aspects of transfusion and hematology and is publicly distributed at home and abroad. The International Journal of Transfusion and Hematology mainly reports on the basic and clinical scientific research results and progress in the field of transfusion and hematology, new experiences, new methods, and new technologies in clinical diagnosis and treatment, introduces domestic and foreign research trends, conducts academic exchanges, and promotes the development of basic and clinical research in the field of transfusion and hematology.
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