The Utilization of Oocyte Cryopreservation Among Indonesia Women

Batara Sirait, Nining Handayani, Ayu Mulia Sundari, T. Wulandari, I. Sini, A. Polim, M. Rizal, A. Boediono
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Abstract

Our study aims to assess the utilization of oocyte cryopreservation (OC) in Indonesian women. Data from 122 women who had undergone OC was retrospectively analyzed from medical records. The baseline profile, clinical characteristics, and main outcomes comprising intentions for oocyte vitrification and outcomes following oocyte warming were examined. Out of 122 women who underwent OC, 49 patients returned and use their cryopreserved oocytes with a median duration of storage was two months. Arranged from the greatest to the least, participants had undergone the cycle of OC due to sperm factor [51 (41.80%)], increased embryo availability [6 (12.1%)], postponement of marriage [6 (12.1%)], social reasons [10 (8.19%)], and other reasons [8 (6.55%)]. Meanwhile, treatment due to advanced maternal age [6 (4.91%)], poor ovarian reserve [6 (4.91%)], cancer [5 (4.09%)], PCOS [2 (1.63%)], and endometriosis [2 (1.63%)] was reported among remaining subjects. Clinical pregnancy was reported in 12 (40.0%) patients constituting of each 6 (50.0%) subjects of day-3 and day-5 embryo transfer, respectively. Our study demonstrated that sperm factor, increased embryo availability, and postponement of marriage is the main reason for women undergoing OC in Indonesia. 
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印度尼西亚妇女卵母细胞冷冻保存的应用
我们的研究旨在评估卵母细胞冷冻保存(OC)在印度尼西亚妇女中的应用。从医疗记录中对122名接受OC的妇女的数据进行回顾性分析。检查了基线概况、临床特征和主要结果,包括卵母细胞玻璃化的意图和卵母细胞加温后的结果。在122名接受OC的女性中,49名患者返回并使用冷冻保存的卵母细胞,平均保存时间为两个月。按照从大到小的顺序,参与者经历了由于精子因素[51(41.80%)]、胚胎可用性增加[6(12.1%)]、婚姻推迟[6(12.1%)],社会原因[10(8.19%)]和其他原因[8(6.55%)]引起的OC周期,其余受试者中报告子宫内膜异位症[2例(1.63%)]。12名(40.0%)患者报告了临床妊娠,其中6名(50.0%)受试者分别接受了第3天和第5天的胚胎移植。我们的研究表明,精子因素、胚胎可用性增加和结婚推迟是印尼女性接受OC的主要原因。
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审稿时长
4 weeks
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