A short review on black fungal mucormycosis accompanied by Post-SARS-CoV-2

Abstract

Many people who have recovered from coronavirus disease 2019 (COVID-19) have recently been diagnosed with black fungus – or mucormycosis – disease. Rhino-orbital mucormycosis is becoming more common in people with COVID-19, particularly in India. On its own, diabetes mellitus is a risk factor for severe COVID-19 and mucormycosis. The goal of this study is to conduct a review of the literature to determine the features of patients with mucormycosis and COVID-19. Increased mucormycosis in India appears to be the result of an unholy trifecta of diabetes (high hereditary incidence), corticosteroid overuse (increased blood glucose and opportunistic fungal infection), and COVID-19 (cytokine storm, lymphopenia, and endothelial damage). To limit the incidence of deadly mucormycosis, all efforts should be made to maintain optimum hyperglycemia, and only prudent evidence-based use of corticosteroids in patients with COVID-19 is advocated. In this review, we emphasize knowledge on diagnosis and therapy regarding black fungal mucormycosis, which is accompanied by post-SARS-CoV-2.