An inclusive exploration of forced degradation analysis of some therapeutic categories of drugs in the last decade

IF 0.1 Q4 MEDICINE, GENERAL & INTERNAL Journal of the Scientific Society Pub Date : 2023-09-01 DOI:10.4103/jss.jss_244_22
T. Narsinghani, J. Tuteja, Anamika Singh
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Abstract

In the pharmaceutical industry, forced degradation tests are used to assess the stability of drug samples. Examining degradation products under stress is beneficial for determining degradation pathways as well as designing and validating appropriate analytical techniques. Forced degradation experiments reveal the molecule's chemical behavior, which aids formulation and packaging creation. The current review examines the forced degradation of a variety of therapeutic classes of medications, including anticancer, antihypertensive, antiviral, CNS pharmaceuticals, and other miscellaneous drugs. During forced degradation analysis, the study examines the degradation behavior of several medications from the abovementioned categories. The findings will likely aid researchers in determining the degradation process of related drugs belonging to the same category.
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来源期刊
Journal of the Scientific Society
Journal of the Scientific Society MEDICINE, GENERAL & INTERNAL-
自引率
33.30%
发文量
19
审稿时长
36 weeks
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