Journey of Immunohistochemistry in General and Oral Pathology: A Review on its Applications and Updates

Abstract

: Immunohistochemistry is a technique with an interesting journey. It is one of the well-established and reliable technique in modern pathology and it is extremely useful in diagnosis of sinister pathologies with perplexing histopathology. Not only does it enhance the diagnostic abilities of a pathologist, but it also has a huge prognostic potential, a great aid in establishing stage of malignancies, determines phenotypic expressions of lymphoid neoplasms and monitors treatment progress and response to therapy. By employing and integrating the basics of varied branches like immunology, histology, microscopy and hematology, it has emerged as a magnificent tool over last few decades, saving pathologists and patients from the impact of serious diseases inflicting the human body. Furthermore, it has contributed immensely to all aspects of diseases related to oral cavity as well. This review has been thus taken to highlight the wide applications of this technique in General and Oral Pathology with an update.