Pathology of Cardiovascular System in Patients with Inflammatory Bowel Diseases

Abstract

The purpose the work was studying of cardiovascular system disease prevalence and structure in persons with the inflammatory bowel diseases (IBD) using Gastroenterology department of the Perm regional hospital as an example. It was the retrospective one-stage research including studying case histories of the patients with ulcerative colitis (UC) and Crohn’s disease (CD) examined and treated in gastroenterological clinic for the period of 2013-2016. There were 291 patients with IBD, chronic cardiovascular pathology was revealed only in 90 patients. Comparative analysis showed that combined diseases were mainly spread in men with UC of middle and advanced age. The most typical for them was combination of UC and ischemic heart disease (50% of cases). Cardiovascular system pathology was 1.5 times more common for women with CD pathology. Besides CD, thromboses of peripheral veins (45% of cases) and myocardial dystrophy (24.5% of cases) were the most frequent pathologies. Due to the small number of patients with IBD and cardiovascular system pathology, it is not possible to claim unambiguously the degree of cardiac disorders in patients with IBD. Thus, it is planned to increase the number of observations to reach statistically optimum conclusion. Studying of this problem is of special practical importance for the possibility to regard patients with IBD as a group of patients with high cardiovascular risk. This will necessitate a number of preventive actions to prevent cardiovascular accidents of fatal and non-fatal